PAGE 1 000 B000000 10/31/2017 000 C000000 0001350869 000 D000000 N 000 E000000 NF 000 F000000 Y 000 G000000 N 000 H000000 N 000 I000000 6.1 000 J000000 A 001 A000000 CLOUGH GLOBAL OPPORTUNITIES FUND 001 B000000 811-21846 001 C000000 8772568445 002 A000000 1290 BROADWAY, SUITE 1100 002 B000000 DENVER 002 C000000 CO 002 D010000 80203 003 000000 N 004 000000 N 005 000000 N 006 000000 N 007 A000000 N 007 B000000 0 008 A000001 CLOUGH CAPITAL PARTNERS LP 008 B000001 A 008 C000001 801-63142 008 D010001 BOSTON 008 D020001 MA 008 D030001 02109 010 A000001 ALPS FUND SERVICES, INC. 010 B000001 84-05730 010 C010001 DENVER 010 C020001 CO 010 C030001 80203 011 A000001 MERRILL LYNCH, PIERCE, FENNER, & SMITH, INC. 011 B000001 8-07221 011 C010001 NEW YORK 011 C020001 NY 011 C030001 10080 012 A000001 DST SYSTEMS, INC. 012 B000001 84-00448 012 C010001 KANSAS CITY 012 C020001 MO 012 C030001 64105 013 A000001 COHEN & CO., LTD. 013 B010001 CLEVELAND 013 B020001 OH 013 B030001 44115 015 A000001 Citibank N.A. Mexico 015 B000001 S 015 C010001 Santa Fe 015 D010001 Mexico PAGE 2 015 E040001 X 015 A000002 Firstrand Bank Limited 015 B000002 S 015 C010002 Johannesburg 015 D010002 South Africa 015 E040002 X 015 A000003 Deutsche Bank AG 015 B000003 S 015 C010003 Amsterdam 015 D010003 The Netherlands 015 E040003 X 015 A000004 Deutsche Bank AG 015 B000004 S 015 C010004 Seoul 015 D010004 Korea 015 D020004 110-752 015 E040004 X 015 A000005 Deutsche Bank AG 015 B000005 S 015 C010005 Milan 015 D010005 Italy 015 D020005 20121 015 E040005 X 015 A000006 Hongkong & Shanghai Banking Corporation Ltd. 015 B000006 S 015 C010006 Auckland 015 D010006 New Zealand 015 D020006 1010 015 E040006 X 015 A000007 Citibank N.A., Brazilian Branch 015 B000007 S 015 C010007 Sao Paulo 015 D010007 Brazil 015 D020007 01311 015 E040007 X 015 A000008 Royal Bank of Canada 015 B000008 S 015 C010008 Toronto 015 D010008 ON Canada 015 D020008 M5V 3L3 015 E040008 X 015 A000009 Standard Chartered Bank (Hong Kong) Limited 015 B000009 S 015 C010009 Kwun Tong 015 D010009 Hong Kong 015 E040009 X 015 A000010 Nordea Bank Norge ASA 015 B000010 S 015 C010010 Oslo 015 D010010 Norway 015 E040010 X PAGE 3 015 A000011 Citibank N.A. 015 B000011 S 015 C010011 Singapore 015 D010011 Singapore 015 D020011 486026 015 E040011 X 015 A000012 BNP Paribas Securities Services 015 B000012 S 015 C010012 Athens 015 D010012 Greece 015 E040012 X 015 A000013 Deutsche Bank AG 015 B000013 S 015 C010013 Moscow 015 D010013 Russia 015 D020013 115035 015 E040013 X 015 A000014 Credit Suisse AG 015 B000014 S 015 C010014 Zurich 015 D010014 Switzerland 015 D020014 8070 015 E040014 X 015 A000015 Deutsche Bank AG 015 B000015 S 015 C010015 Makati City 015 D010015 Phillipines 015 D020015 1226 015 E040015 X 015 A000016 Deutsche Bank AG 015 B000016 S 015 C010016 Jakarta 015 D010016 Indonesia 015 D020016 10310 015 E040016 X 015 A000017 Deutsche Bank AG 015 B000017 S 015 C010017 Kuala Lumpur 015 D010017 Malaysia 015 D020017 50250 015 E040017 X 015 A000018 Deutsche Bank AG 015 B000018 S 015 C010018 Eschborn 015 D010018 Germany 015 E040018 X 015 A000019 HSBC Shanghai 015 B000019 S 015 C010019 Shanghai 015 D010019 China 015 D020019 200120 PAGE 4 015 E040019 X 015 A000020 Deutsche Bank Sociedad Anonima ESPA 015 B000020 S 015 C010020 Madrid 015 D010020 Spain 015 D020020 28020 015 E040020 X 015 A000021 HSBC Sydney 015 B000021 S 015 C010021 Sydney 015 D010021 Australia 015 E040021 X 015 A000022 Nordea Bank AB 015 B000022 S 015 C010022 Stockholm 015 D010022 Sweden 015 E040022 X 015 A000023 Nordea Bank Finland PLC 015 B000023 S 015 C010023 Helsinki 015 D010023 Finland 015 E040023 X 015 A000024 Standard Chartered Bank (Taiwan) Limited 015 B000024 S 015 C010024 Taipei 015 D010024 Taiwan 015 E040024 X 015 A000025 Standard Chartered Bank (Thailand) PLC 015 B000025 S 015 C010025 Bangkok 015 D010025 Thailand 015 D020025 10500 015 E040025 X 015 A000026 State Street Bank and Trust Company 015 B000026 S 015 C010026 Edinburgh 015 D010026 Scotland 015 D020026 EH5 2AW 015 E040026 X 015 A000027 The Hongkong and Shanghai Banking Corporation 015 B000027 S 015 C010027 Tokyo 015 D010027 Japan 015 D020027 1030027 015 E040027 X 015 A000028 State Street Corporation 015 B000028 C 015 C010028 Boston 015 C020028 MA 015 C030028 02111 015 E020028 X PAGE 5 015 A000029 Deutsche Bank S.P.A 015 B000029 S 015 C010029 Mumbai 015 D010029 India 015 D020029 400063 015 E040029 X 015 A000030 Nordea Bank Danmark 015 B000030 S 015 C010030 Copenhagen C 015 D010030 Denmark 015 D020030 0900 015 E040030 X 018 000000 Y 019 A000000 N 019 B000000 0 020 A000001 JEFFERIES & CO., INC. 020 B000001 92-2622900 020 C000001 228 020 A000002 KNIGHT EQUITY MARKETS LP 020 B000002 22-3660471 020 C000002 218 020 A000003 BNP PARIBAS SECURITIES CORP. 020 B000003 13-3459854 020 C000003 143 020 A000004 CITIGROUP GLOBAL MARKETS, INC. 020 B000004 11-2418191 020 C000004 132 020 A000005 MERRILL LYNCH PROFESSIONAL CLEARING CORP. 020 B000005 12-3247006 020 C000005 96 020 A000006 UBS SECURITIES LLC 020 B000006 13-3873456 020 C000006 95 020 A000007 O'NEIL SECURITIES, INC. 020 B000007 95-2269163 020 C000007 92 020 A000008 JP MORGAN CHASE & CO. 020 B000008 13-2624428 020 C000008 85 020 A000009 CLSA AMERICAS, LLC 020 B000009 46-0882815 020 C000009 80 020 A000010 MORGAN STANLEY & CO., INC. 020 B000010 13-2655998 020 C000010 80 021 000000 1887 022 A000001 BLACKROCK INSTITUTIONAL LIQUIDITY FUNDS 022 C000001 776994 022 D000001 751206 022 A000002 ROBERT W. BAIRD & CO., INC. 022 B000002 39-6037917 PAGE 6 022 C000002 259937 022 D000002 351102 022 A000003 MORGAN STANLEY & CO., INC. 022 B000003 13-2655998 022 C000003 115132 022 D000003 46437 022 A000004 JEFFRIES & CO., INC. 022 B000004 95-2622900 022 C000004 82854 022 D000004 32255 022 A000005 RBC CAPITAL MARKETS LLC 022 B000005 41-1416330 022 C000005 77201 022 D000005 32319 022 A000006 GOLDMAN SACHS & CO. 022 B000006 13-5108880 022 C000006 21884 022 D000006 72242 022 A000007 LEGG MASON INVESTOR SERVICES LLC 022 B000007 13-4146187 022 C000007 36516 022 D000007 20977 022 A000008 DEUTSCHE BANK SECURITIES, INC. 022 B000008 13-2730828 022 C000008 31848 022 D000008 25607 022 A000009 SUSQUEHANNA FINANCIAL GROUP LLLP 022 B000009 23-2626048 022 C000009 14814 022 D000009 16399 022 A000010 CREDIT SUISSE SECURITIES (USA) LLC 022 B000010 05-0546650 022 C000010 22148 022 D000010 3497 023 C000000 1460790 023 D000000 1354099 024 000000 Y 025 A000001 CITIGROUP GLOBAL MARKETS, INC. 025 B000001 11-2418191 025 C000001 E 025 D000001 21574 025 A000002 CITIGROUP GLOBAL MARKETS, INC. 025 B000002 11-2418191 025 C000002 D 025 D000002 8032 025 A000003 MORGAN STANLEY & CO., INC. 025 B000003 13-2655998 025 C000003 D 025 D000003 5012 025 A000004 GOLDMAN SACHS & CO. 025 B000004 13-5108880 PAGE 7 025 C000004 D 025 D000004 8504 025 A000005 BLACKROCK INSTITUTIONAL LIQUIDITY FUNDS 025 C000005 D 025 D000005 31484 025 A000006 RBC CAPITAL MARKETS LLC 025 B000006 41-1416330 025 C000006 D 025 D000006 4988 025 A000007 JP MORGAN CHASE & CO. 025 B000007 13-2624428 025 C000007 D 025 D000007 8127 025 A000008 JP MORGAN CHASE & CO. 025 B000008 13-2624428 025 C000008 E 025 D000008 16017 025 A000009 BANK OF AMERICA CORPORATION 025 B000009 94-1687665 025 C000009 E 025 D000009 21959 025 A000010 BANK OF AMERICA CORPORATION 025 B000010 94-1687665 025 C000010 D 025 D000010 4951 026 A000000 N 026 B000000 Y 026 C000000 Y 026 D000000 Y 026 E000000 Y 026 F000000 N 026 G010000 N 026 G020000 N 026 H000000 N 027 000000 N 045 000000 Y 046 000000 N 047 000000 Y 048 000000 1.000 048 A010000 0 048 A020000 0.000 048 B010000 0 048 B020000 0.000 048 C010000 0 048 C020000 0.000 048 D010000 0 048 D020000 0.000 048 E010000 0 048 E020000 0.000 048 F010000 0 048 F020000 0.000 PAGE 8 048 G010000 0 048 G020000 0.000 048 H010000 0 048 H020000 0.000 048 I010000 0 048 I020000 0.000 048 J010000 0 048 J020000 0.000 048 K010000 0 048 K020000 0.000 049 000000 N 050 000000 N 051 000000 N 052 000000 N 053 A000000 N 054 A000000 Y 054 B000000 Y 054 C000000 Y 054 D000000 Y 054 E000000 Y 054 F000000 N 054 G000000 Y 054 H000000 Y 054 I000000 N 054 J000000 Y 054 K000000 Y 054 L000000 N 054 M000000 Y 054 N000000 N 054 O000000 Y 055 A000000 Y 055 B000000 Y 056 000000 Y 057 000000 N 058 A000000 N 059 000000 Y 060 A000000 Y 060 B000000 Y 061 000000 0 062 A000000 N 062 B000000 0.0 062 C000000 0.0 062 D000000 0.0 062 E000000 0.0 062 F000000 0.0 062 G000000 0.0 062 H000000 0.0 062 I000000 0.0 062 J000000 0.0 062 K000000 0.0 062 L000000 0.0 PAGE 9 062 M000000 0.0 062 N000000 0.0 062 O000000 0.0 062 P000000 0.0 062 Q000000 0.0 062 R000000 0.0 066 A000000 Y 066 B000000 N 066 C000000 N 066 D000000 N 066 E000000 N 066 F000000 N 066 G000000 Y 067 000000 N 068 A000000 N 068 B000000 N 069 000000 N 070 A010000 Y 070 A020000 N 070 B010000 Y 070 B020000 N 070 C010000 Y 070 C020000 N 070 D010000 Y 070 D020000 N 070 E010000 Y 070 E020000 Y 070 F010000 Y 070 F020000 N 070 G010000 Y 070 G020000 N 070 H010000 Y 070 H020000 N 070 I010000 N 070 I020000 N 070 J010000 Y 070 J020000 Y 070 K010000 Y 070 K020000 Y 070 L010000 Y 070 L020000 Y 070 M010000 Y 070 M020000 Y 070 N010000 Y 070 N020000 Y 070 O010000 Y 070 O020000 Y 070 P010000 N 070 P020000 N 070 Q010000 N 070 Q020000 N PAGE 10 070 R010000 Y 070 R020000 Y 071 A000000 1339791 071 B000000 1416715 071 C000000 813642 071 D000000 165 072 A000000 12 072 B000000 8171 072 C000000 9624 072 D000000 0 072 E000000 347 072 F000000 9537 072 G000000 3050 072 H000000 0 072 I000000 0 072 J000000 0 072 K000000 0 072 L000000 0 072 M000000 156 072 N000000 0 072 O000000 0 072 P000000 5698 072 Q000000 0 072 R000000 0 072 S000000 163 072 T000000 0 072 U000000 0 072 V000000 0 072 W000000 496 072 X000000 19100 072 Y000000 0 072 Z000000 -958 072AA000000 39959 072BB000000 0 072CC010000 68778 072CC020000 0 072DD010000 55212 072DD020000 0 072EE000000 0 073 A010000 1.0708 073 A020000 0.0000 073 B000000 0.0000 073 C000000 0.0000 074 A000000 2227 074 B000000 0 074 C000000 0 074 D000000 270229 074 E000000 9857 074 F000000 524313 074 G000000 0 074 H000000 0 PAGE 11 074 I000000 76062 074 J000000 4199 074 K000000 0 074 L000000 2135 074 M000000 103854 074 N000000 992876 074 O000000 769 074 P000000 841 074 Q000000 0 074 R010000 0 074 R020000 74569 074 R030000 0 074 R040000 293336 074 S000000 0 074 T000000 623361 074 U010000 51559 074 U020000 0 074 V010000 12.09 074 V020000 0.00 074 W000000 0.0000 074 X000000 0 074 Y000000 0 075 A000000 0 075 B000000 589584 076 000000 11.42 077 A000000 Y 077 B000000 Y 077 Q010000 Y 078 000000 N 080 A000000 AXIS Insurance Company 080 C000000 2500 081 A000000 Y 081 B000000 2 082 A000000 Y 082 B000000 25 083 A000000 N 084 A000000 N 085 A000000 Y 085 B000000 N 086 A010000 0 086 A020000 0 086 B010000 15 086 B020000 138 086 C010000 0 086 C020000 0 086 D010000 0 086 D020000 0 086 E010000 0 086 E020000 0 086 F010000 0 086 F020000 0 PAGE 12 087 A010000 COMMON STOCK 087 A020000 18914E106 087 A030000 GLO 088 A000000 N 088 B000000 N 088 C000000 N 088 D000000 N SIGNATURE Jill Kerschen TITLE Assistant Treasurer