October 1, 2012


Securities & exchange Commission
450 Fifth Street, NW
Washington, DC 20549

Attn.: Document Control



RE:	American Depositary Shares
evidenced by the American Depositary
Receipts each representing Two (2) Ordinary
Shares of XTL Biopharmaceuticals Ltd.
(Form F-6 File No. 333-147677)


Ladies and Gentlemen:

Pursuant to Rule 424(b)(3) under the
Securities Act of 1933, as amended, on
behalf of The Bank of New York, as
Depositary for securities against which
American Depositary Receipts are to be
issued, we attach a copy of the new
prospectus (Prospectus) reflecting in number
of ordinary shares represented by one
American Depositary Share (the Ratio).

As required by Rule 424(e), the upper right
hand corner of the Prospectus cover page has
a reference to Rule 424(b)(3) and to the file
number of the registration statement to which
the Prospectus relates.

Pursuant to Section III B of the General
Instructions to the Form F-6 Registration
Statement, the Prospectus consists of the
ADR certificate with revised ratio for XTL
Biopharmaceuticals Ltd.

The Prospectus has been revised to reflect
the new ratio and has been overstampted
with:

Effective October 4, 2012 the Companys
American Depositary Share (ADS) Ratio
Changed from 1:2 (One ADS
Representing Two deposited Shares to
1:20 (One ADS Representing Twenty
deposited Shares).


Please contact me with any questions or
comments at 212 815-8223

Agness Moskovits
The Bank of New York Mellon - ADR
Division
Encl.
CC: Paul Dudek, Esq. (Office of International
Corporate Finance)









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