Ownership Submission
FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Cantwell Mark Joseph
 2. Date of Event Requiring Statement (Month/Day/Year)
02/28/2006		 3. Issuer Name and Ticker or Trading Symbol
ADVENTRX PHARMACEUTICALS INC [ANX]
(Last)
(First)
(Middle)
6725 MESA RIDGE RD., SUITE 100		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
VP, Research & Development
 5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

SAN DIEGO, CA 92121		 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Option to Purchase Common Stock 11/03/2004(1) 12/30/2008 Common Stock 50,000 $ 1.4 D  
Option to Purchase Common Stock 01/01/2006(2) 07/13/2015 Common Stock 50,000 $ 2.3 D  
Option to Purchase Common Stock 01/01/2007(3) 01/01/2016 Common Stock 50,000 $ 4.75 D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Cantwell Mark Joseph
6725 MESA RIDGE RD.
SUITE 100
SAN DIEGO, CA 92121		       VP, Research & Development  

Signatures

/s/ Mark J. Cantwell 03/09/2006
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) This option is fully vested as the date of this report.
(2) This option vested and became exercisable with respect to one-fourth of the shares on January 1, 2006, and will vest and become exercisable with respect to one-forty eight of the shares at the end of each successive month after January 1, 2006.
(3) This option will vest and become exercisable with respect to one-fourth of the shares on January 1, 2007 and as to one-forty-eighth of the shares at the end of each successive month after January 1, 2007.

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