As filed with the Securities and Exchange Commission on May 23, 2013
================================================================================
                                                1933 Act File No. 333-__________
                                                     1940 Act File No. 811-22795


                    U.S. SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                    FORM N-2

(Check appropriate box or boxes)


[X] REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933
[ ] Pre-Effective Amendment No.
[ ] Post-Effective Amendment No. _

and

[ ] REGISTRATION STATEMENT UNDER THE INVESTMENT COMPANY ACT OF 1940
[X] Amendment No. 4


           First Trust Intermediate Duration Preferred & Income Fund
         Exact Name of Registrant as Specified in Declaration of Trust


           120 East Liberty Drive, Suite 400, Wheaton, Illinois 60187
 Address of Principal Executive Offices (Number, Street, City, State, Zip Code)


                                 (630) 765-8000
               Registrant's Telephone Number, including Area Code


                             W. Scott Jardine, Esq.
                          First Trust Portfolios L.P.
                       120 East Liberty Drive, Suite 400
                            Wheaton, Illinois 60187

 Name and Address (Number, Street, City, State, Zip Code) of Agent for Service


                          Copies of Communications to:

          Eric F. Fess, Esq.                        David E. Wohl

        Chapman and Cutler LLP                Weil, Gotshal & Manges LLP
        111 West Monroe Street                     767 Fifth Avenue
       Chicago, Illinois 60603                 New York, New York 10153






Approximate Date of Proposed Public Offering: As soon as practicable after the
effective date of this Registration Statement

---------------

If any of the securities being registered on this form are offered on a delayed
or continuous basis in reliance on Rule 415 under the Securities Act of 1933,
other than securities offered in connection with a dividend reinvestment plan,
check the following box. [ ]

It is proposed that this filing will become effective (check appropriate box)

   [ ] when declared effective pursuant to section 8(c)


If appropriate, check the following box:


   [ ] This post-effective amendment designates a new effective date for a
         previously filed registration statement.


   [X] This form is filed to register additional securities for an offering
       pursuant to Rule 462(b) under the Securities Act and the Securities Act
       registration statement number of the earlier effective registration
       statement for the same offering is 333-186412

---------------





CALCULATION OF REGISTRATION FEE UNDER THE SECURITIES ACT OF 1933

================================================================================


------------------------  ----------------------  ---------------------  ----------------------  ---------------------
                                                    Proposed Maximum       Proposed Maximum
  Title of Securities         Amount Being           Offering Price       Aggregate Offering     Amount of Registration
   Being Registered            Registered               Per Unit               Price(1)                  Fee(2)
------------------------  ----------------------  ---------------------  ----------------------  ---------------------
                                                                                          
 Common Shares, $0.01
       par value               5,219,007                $25.00               $130,475,175             $17,796.82
------------------------  ----------------------  ---------------------  ----------------------  ---------------------


(1) All of which may be purchased pursuant to an over-allotment option of
    8,419,007 shares granted by the Registrant to the Underwriters.

(2) Estimated solely for the purpose of determining the registration fee.

================================================================================


                EXPLANATORY NOTE AND INCORPORATION BY REFERENCE

      This Registration Statement is being filed pursuant to Rule 462(b) under
the Securities Act of 1933, as amended. The contents of the Registration
Statement on Form N-2 (Reg. No. 333-186412) filed by First Trust Intermediate
Duration Preferred & Income Fund (the "Registrant") with the Securities and
Exchange Commission, declared effective May 23, 2013, are incorporated herein by
reference. On May 23, 2013, the Registrant registered 60,000,000 common shares
in Pre-Effective Amendment No. 3 to the Registrant's Registration Statement
filed on Form N-2. When the common shares previously registered are combined
with the common shares registered herein, the total number of shares registered
by the Registrant is 65,219,007 shares. Any required consents are listed on an
Exhibit Index attached hereto and are filed herewith.





                           PART C - OTHER INFORMATION

Item 25: Financial Statements and Exhibits

1.     Financial Statements:

      Registrant has not conducted any business as of the date of this filing,
other than in connection with its organization. Financial Statements indicating
that the Registrant has met the net worth requirements of Section 14(a) of the
Investment Company Act of 1940 were filed with Pre-effective Amendment No. 2 to
the Registration Statement on Form N-2 (File No. 333-186412).

2.     Exhibits:

a.    Declaration of Trust dated January 28, 2013. (1)

b.    By-Laws of Fund. (3)

c.    None.

d.    None.

e.    Terms and Conditions of the Dividend Reinvestment Plan. (4)

f.    None.

g.1   Form of Investment Management Agreement between Registrant and First Trust
      Advisors L.P. (3)

g.2   Form of Sub-Advisory Agreement between Registrant, First Trust Advisors
      L.P. and Stonebridge Advisors LLC. (3)

h.1   Form of Underwriting Agreement. (3)

h.2   Form of Master Agreement Among Underwriters. (3)

h.3   Form of Master Selected Dealers Agreement. (3)

i.    None.

j.    Form of Custodian Agreement between Registrant and Fund Custodian. (3)

k.1   Form of Transfer Agency and Service Agreement between Registrant and Fund
      Transfer Agent. (3)

k.2   Form of Administrative Agency Agreement. (3)

k.3   Form of Structuring Fee Agreement with Morgan Stanley & Co. LLC. (3)





k.4   Form of Syndication Fee Agreement with Morgan Stanley & Co. LLC. (3)

k.5   Form of Structuring Fee Agreement with Citigroup Global Markets Inc. (3)

k.6   Form of Structuring Fee Agreement with Merrill Lynch, Pierce, Fenner &
      Smith Incorporated. (3)

k.7   Form of Structuring Fee Agreement with RBC Capital Markets, LLC. (3)

k.8   Form of Structuring Fee Agreement with Oppenheimer & Co. Inc. (3)

k.9   Form of Structuring Fee Agreement with Comerica Securities, Inc. (3)

k.10  Form of Fee Agreement with Pershing LLC. (3)

k.11  Form of Structuring Fee Agreement with Sterne, Agee & Leach, Inc. (3)

k.12  Form of Structuring Fee Agreement with Janney Montgomery Scott LLC. (3)

k.13  Form of Structuring Fee Agreement with J.J.B. Hilliard, W.L. Lyons LLC.
      (3)

k.14  Form of Structuring Fee Agreement with Southwest Securities. (3)

k.15  Form of Structuring Fee Agreement with BB&T Capital Markets, a division of
      BB&T Securities, LLC. (3)

k.16  Form of Structuring Fee Agreement with qualifying underwriters. (3)

l.1   Opinion and consent of Chapman and Cutler LLP. (4)

l.2   Opinion and consent of Bingham McCutchen LLP. (4)

m.    None.

n.    Consent of Independent Registered Public Accounting Firm. (4)

o.    None.

p.    Subscription Agreement between Registrant and First Trust Advisors L.P.
      (3)

q.    None.

r.1   Code of Ethics of Registrant. (3)

r.2   Code of Ethics of First Trust Portfolios L.P. (3)

r.3   Code of Ethics of First Trust Advisors L.P. (3)





r.4.  Code of Ethics of Stonebridge Advisors LLC. (3)

s.    Powers of Attorney. (2)

-------------------------------

(1)   Filed on February 4, 2013 as Exhibit a. to Registrant's Registration
      Statement on Form N-2 (File No. 333-186412) and incorporated herein by
      reference.

(2)   Filed on April 5, 2013 as Exhibit s. to Registrant's Registration
      Statement on Form N-2 (File No. 333-186412) and incorporated herein by
      reference.

(3)   Filed on May 23, 2013 in Pre-Effective Amendment No. 3 to Registrant's
      Registration Statement on Form N-2 (File No. 333-186412) and incorporated
      herein by reference.

(4)   Filed herewith.


Item 26: Marketing Arrangements

      See the Form of Underwriting Agreement, the Form of Master Agreement Among
Underwriters, the Form of Master Selected Dealers Agreement, the Form of
Structuring Fee Agreement of Morgan Stanley & Co. LLC, the Form of Syndication
Fee Agreement of Morgan Stanley & Co. LLC, the Form of Structuring Fee Agreement
of Citigroup Global Markets Inc., the Form of Structuring Fee Agreement of
Merrill Lynch, Pierce, Fenner & Smith Incorporated, the Form of Structuring Fee
Agreement of RBC Capital Markets, LLC, the Form of Structuring Fee Agreement of
Oppenheimer & Co. Inc., the Form of Structuring Fee Agreement of Comerica
Securities, Inc., the Form of Fee Agreement of Pershing LLC, the Form of
Structuring Fee Agreement of Sterne, Agee & Leach, Inc., the Form of Structuring
Fee Agreement with Janney Montgomery Scott LLC, the Form of Structuring Fee
Agreement with J.J.B. Hilliard, W.L. Lyons LLC, the Form of Structuring Fee
Agreement with Southwest Securities, the Form of Structuring Fee Agreement with
BB&T Capital Markets, a division of BB&T Securities, LLC and the Form of
Structuring Fee Agreement with qualifying underwriters filed as Exhibit (h)(1),
Exhibit (h)(2), Exhibit (h)(3), Exhibit (k)(3), Exhibit (k)(4), Exhibit (k)(5),
Exhibit (k)(6), Exhibit (k)(7), Exhibit (k)(8), Exhibit (k)(9), Exhibit (k)(10),
Exhibit (k)(11), Exhibit (k)(12), Exhibit (k)(13), Exhibit (k)(14), Exhibit
(k)(15), and Exhibit (k)(16), respectively, to Registrant's Registration
Statement on Form N-2 (File No. 333-186412).


Item 27:  Other Expenses of Issuance and Distribution

---------------------------------------------------------- --------------------
Securities and Exchange Commission Fees                    $  222,400
---------------------------------------------------------- --------------------
Financial Industry Regulatory Authority, Inc. Fees         $  225,500
---------------------------------------------------------- --------------------
Printing and Engraving Expenses                            $  200,000
---------------------------------------------------------- --------------------
Legal Fees                                                 $  800,000
---------------------------------------------------------- --------------------
Listing Fees                                               $   40,000
---------------------------------------------------------- --------------------
Accounting Expenses                                        $   20,500
---------------------------------------------------------- --------------------
Blue Sky Filing Fees and Expenses                          $       --
---------------------------------------------------------- --------------------
Miscellaneous Expenses                                     $  309,400
---------------------------------------------------------- --------------------
Total                                                      $1,817,800
---------------------------------------------------------- --------------------


Item 28: Persons Controlled by or under Common Control with Registrant

    Not applicable.


Item 29:  Number of Holders of Securities

    At May 23, 2013

---------------------------------- -----------------------------------------
Title of Class                     Number of Record Holders
---------------------------------- -----------------------------------------
Common Shares, $0.01 par value     1
---------------------------------- -----------------------------------------





Item 30: Indemnification

Section 9.5 of the Registrant's Declaration of Trust provides as follows:

      Indemnification and Advancement of Expenses. Subject to the exceptions and
limitations contained in this Section 9.5, every person who is, or has been, a
Trustee, officer or employee of the Trust, including persons who serve at the
request of the Trust as directors, trustees, officers, employees or agents of
another organization in which the Trust has an interest as a shareholder,
creditor or otherwise (hereinafter referred to as a "Covered Person"), shall be
indemnified by the Trust to the fullest extent permitted by law against
liability and against all expenses reasonably incurred or paid by him in
connection with any claim, action, suit or proceeding in which he becomes
involved as a party or otherwise by virtue of his being or having been such a
Trustee, director, officer, employee or agent and against amounts paid or
incurred by him in settlement thereof.

      No indemnification shall be provided hereunder to a Covered Person to the
extent such indemnification is prohibited by applicable federal law.

      The rights of indemnification herein provided may be insured against by
policies maintained by the Trust, shall be severable, shall not affect any other
rights to which any Covered Person may now or hereafter be entitled, shall
continue as to a person who has ceased to be such a Covered Person and shall
inure to the benefit of the heirs, executors and administrators of such a
person.

      Subject to applicable federal law, expenses of preparation and
presentation of a defense to any claim, action, suit or proceeding subject to a
claim for indemnification under this Section 9.5 shall be advanced by the Trust
prior to final disposition thereof upon receipt of an undertaking by or on
behalf of the recipient to repay such amount if it is ultimately determined that
he is not entitled to indemnification under this Section 9.5.

      To the extent that any determination is required to be made as to whether
a Covered Person engaged in conduct for which indemnification is not provided as
described herein, or as to whether there is reason to believe that a Covered
Person ultimately will be found entitled to indemnification, the Person or
Persons making the determination shall afford the Covered Person a rebuttable
presumption that the Covered Person has not engaged in such conduct and that
there is reason to believe that the Covered Person ultimately will be found
entitled to indemnification.

      As used in this Section 9.5, the words "claim," "action," "suit" or
"proceeding" shall apply to all claims, demands, actions, suits, investigations,
regulatory inquiries, proceedings or any other occurrence of a similar nature,
whether actual or threatened and whether civil, criminal, administrative or
other, including appeals, and the words "liability" and "expenses" shall include
without limitation, attorneys' fees, costs, judgments, amounts paid in
settlement, fines, penalties and other liabilities.

      Section 8 of the Form of Underwriting Agreement filed as Exhibit (h)(1) to
this Registration Statement provides for each of the parties thereto, including
the Registrant and the underwriters, to indemnify the others, their directors,
officers, agents, affiliates and persons who control them against certain





liabilities in connection with the offering described herein, including
liabilities under the federal securities laws.

Item 31: Business and Other Connections of Investment Advisers

The information in the Statement of Additional Information under the captions
"Management of the Fund - Trustees and Officers" and "Sub-Advisor," and the Form
ADV of Stonebridge Advisors LLC (File No. 801-63899) filed with the Commission
are hereby incorporated by reference.


Item 32: Location of Accounts and Records.

First Trust Advisors L.P. maintains the Declaration of Trust, By-Laws, minutes
of trustees and shareholders meetings and contracts of the Registrant, all
advisory material of the investment adviser, all general and subsidiary ledgers,
journals, trial balances, records of all portfolio purchases and sales, and all
other required records.


Item 33: Management Services

Not applicable.


Item 34: Undertakings

1.      Registrant undertakes to suspend the offering of its shares until it
        amends its prospectus if (1) subsequent to the effective date of its
        Registration Statement, the net asset value declines more than 10
        percent from its net asset value as of the effective date of the
        Registration Statement, or (2) the net asset value increases to an
        amount greater than its net proceeds as stated in the prospectus.

2.     Not applicable.


3.     Not applicable.


4.     Not applicable.


5. The Registrant undertakes that:

a.      For purposes of determining any liability under the Securities Act of
        1933, the information omitted from the form of prospectus filed as part
        of a registration statement in reliance upon Rule 430A and contained in
        the form of prospectus filed by the Registrant under Rule 497(h) under
        the Securities Act of 1933 shall be deemed to be part of the
        Registration Statement as of the time it was declared effective; and

b.      For the purpose of determining any liability under the Securities Act of
        1933, each post-effective amendment that contains a form of prospectus
        shall be deemed to be a new registration statement relating to the
        securities offered therein, and the offering of the securities at that
        time shall be deemed to be the initial bona fide offering thereof.





6.      The Registrant undertakes to send by first class mail or other means
        designed to ensure equally prompt delivery, within two business days of
        receipt of a written or oral request, any Statement of Additional
        Information.





                                   SIGNATURES

      Pursuant to the requirements of the Securities Act of 1933 and the
Investment Company Act of 1940, the Registrant has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in this City of Wheaton, and State of Illinois, on the 23nd day of
May, 2013.

                                            FIRST TRUST INTERMEDIATE DURATION
                                            PREFERRED & INCOME FUND



                                            By: /s/ Mark R. Bradley
                                                ------------------------------
                                                Mark R. Bradley, President and
                                                Chief Executive Officer


      Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement has been signed below by the following persons in the
capacities and on the date indicated.



-------------------------------------   -----------------------------------   ------------------------------------
                                                                        
Signature                               Title                                 Date
-------------------------------------   -----------------------------------   ------------------------------------
                                        President and Chief Executive         May 23, 2013
/s/ Mark R. Bradley                     Officer
---------------------------------       (Principal Executive Officer)
 Mark R. Bradley
-------------------------------------   -----------------------------------   ------------------------------------
                                        Chief Financial Officer, Chief        May 23, 2013
                                        Accounting Officer and
/s/ James M. Dykas                      Treasurer (Principal Financial and
---------------------------------       Accounting Officer)
 James M. Dykas
-------------------------------------   -----------------------------------   ------------------------------------
James A. Bowen(1)                       Chairman of the Board and Trustee )
-------------------------------------   -----------------------------------
Richard E. Erickson(1)                  Trustee                           )   By: /s/ W. Scott Jardine
-------------------------------------   -----------------------------------       -----------------------------
Thomas R. Kadlec(1)                     Trustee                           )            W. Scott Jardine
-------------------------------------   -----------------------------------            Attorney-In-Fact
Robert F. Keith(1)                      Trustee                           )            May 23, 2013
-------------------------------------   -----------------------------------
Niel B. Nielson(1)                      Trustee                           )
-------------------------------------   -----------------------------------   ------------------------------------


---------------

(1) Original powers of attorney authorizing James A. Bowen, Mark R. Bradley, W.
Scott Jardine, Kristi A. Maher and Eric F. Fess to execute Registrant's
Registration Statement, and Amendments thereto, for each of the trustees of the
Registrant on whose behalf this Registration Statement is filed, were previously
executed and are filed as Exhibit s. to the Registrant's Registration Statement
on Form N-2 (File No. 333-186412).





                               INDEX TO EXHIBITS

e.   Terms and Conditions of the Dividend Reinvestment Plan.

l.1  Opinion and consent of Chapman and Cutler LLP.

l.2  Opinion and consent of Bingham McCutchen LLP.

n.   Consent of Independent Registered Public Accounting Firm.