Filed Pursuant to Rule 424(b)(3)
Registration No. 333-127857
ADVENTRX PHARMACEUTICALS, INC.
SUPPLEMENT TO PROSPECTUS DATED SEPTEMBER 8, 2005
This Supplement, dated May 8, 2007, supplements certain information contained in our
prospectus dated September 8, 2005 (the “Prospectus”). This supplement is not complete without, and
may not be delivered or utilized except in connection with, the Prospectus, including any
amendments or supplements thereto.
The information contained in the table under the caption “Selling Security Holders” beginning
on page 10 of the Prospectus is hereby supplemented by: (i) adding to the table the selling
security holders set forth below under Schedule 1, and (ii) amending and restating the holdings of
the selling security holders set forth below under Schedule 2.
SCHEDULE 1
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Shares Owned |
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Percent Owned |
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Shares Owned Upon |
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Percent |
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Before |
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Shares Being |
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Completion Of |
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Owned After |
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| Name |
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Offering(1) |
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Offering(2) |
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Offered |
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Offering |
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Offering(2) |
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Vicis Capital
Master Fund |
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1,031,351 |
(29) |
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1.15 |
%† |
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910,151 |
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121,200 |
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† |
Matthew Balk |
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3,690,509 |
(30) |
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4.1 |
%† |
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250,000 |
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3,440,509 |
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3.8 |
%† |
Jason Adelman |
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866,246 |
(31) |
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1.0 |
%† |
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250,000 |
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616,246 |
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(29) Consists of 1,031,351 shares of common stock issuable upon exercise of warrants held
by this entity, 910,151 of which will be offered.
(30) Includes 384,447 shares of common stock issuable upon exercise of warrants held by
this person, 250,000 of which will be offered.
(31) Includes 421,946 shares of common stock issuable upon exercise of warrants held by this
person, 250,000 of which will be offered.
† The percentage ownership of common stock is based on 89,706,739 shares of our common stock
outstanding as of April 30, 2007. Options and warrants to purchase our common stock that are
presently exercisable or exercisable within 60 days of April 30, 2007, even if such options or
warrants may otherwise be subject to restriction on exercise, are included in the total number of
shares beneficially owned for the selling security holder holding those options or warrants and are
considered outstanding for the purpose of calculating percentage ownership of that particular
selling security holder.
SCHEDULE 2
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Shares Owned |
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Percent Owned |
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Shares |
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Shares Owned Upon |
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Percent |
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Before |
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Before |
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Being |
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Completion Of |
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Owned After |
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Offering(1) |
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Offering(2) |
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Offered |
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Offering |
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Offering(2) |
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North Sound
Legacy
Institutional Fund
LLC |
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North Sound Legacy
International Ltd. |
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Information concerning the selling security holders is based upon information provided to us
by the security holders. This information may change from time to time and any changed information
will be set forth in future prospectus supplements, if and when necessary. Additionally, the
selling security holders identified above and in the Prospectus may have sold, transferred or
otherwise disposed of all or a portion of their shares of our common stock since the date on which
they last provided us with information about their holdings.