Proxy Statement Pursuant to Section 14(a) of the
                         Securities Exchange Act of 1934

Filed by the Registrant |X|

Filed by a Party other than the Registrant |_|

Check the appropriate box:

|X| Preliminary Proxy Statement                        |_| Confidential, For Use
                                                           of the Commission
                                                           Only (as permitted by
                                                           Rule 14a-6(e)(2))

|_| Definitive Proxy Statement

|_| Definitive Additional Materials

|_| Soliciting Material Pursuant to Rule 14a-12

                            Milestone Scientific Inc.
                (Name of Registrant as Specified in Its Charter)
    (Name of Person(s) Filing Proxy Statement, if Other than the Registrant)

Payment of Filing Fee (Check the appropriate box):

|X| No fee required.



                            MILESTONE SCIENTIFIC INC.

      Notice of Special Meeting of Stockholders to be held on December 9, 2003

                                  ------------

      A Special Meeting of Stockholders of Milestone Scientific Inc. (the
"Company") will be held at the offices of Morse, Zelnick, Rose & Lander, LLP,
405 Park Avenue, Suite 1401, New York, New York 10022 on Tuesday, December 9,
2003 at 9:00 a.m., Eastern Standard Time, for the purpose of considering and
acting upon the following:

      1.    Approval of an amendment to the Company's Certificate of
            Incorporation to effect a reverse stock split of its common stock at
            a ratio no greater than one-for-ten at any time prior to December
            31, 2004, at the sole discretion of the Company's board of
            directors, in connection with an underwritten public offering by the
            Company.

      2.    Any and all matters incident to the foregoing, and such other
            business as may legally come before the meeting and any adjournments
            or postponements thereof.

      The Board of Directors has fixed the close of business on November 7, 2003
as the record date for determining the stockholders having the right to notice
of and to vote at the meeting.

                                           By order of the Board of Directors


                                           Leonard Osser
                                           Chairman of the Board

Livingston, New Jersey
November __, 2003

--------------------------------------------------------------------------------
IMPORTANT:  Every stockholder, whether or not he, she or it expects to attend
            the annual meeting in person, is urged to execute the Proxy and
            return it promptly in the enclosed business reply envelope.

            Sending in your Proxy will not prevent you from voting your stock at
            the meeting if you desire to do so, as your Proxy is revocable at
            your option.

            We would appreciate your giving this matter your prompt attention.



                            MILESTONE SCIENTIFIC INC.

                                   ----------

                                 PROXY STATEMENT
                                       For
                         Special Meeting of Stockholders
                           To be Held December 9, 2003

                                   ----------

      Proxies in the form enclosed with this statement are being solicited by us
to be used at the Special Meeting of Stockholders to be held at the offices of
Morse, Zelnick, Rose & Lander, LLP, 405 Park Avenue, Suite 1401, New York, New
York 10022 on Tuesday, December 9, 2003 at 9:00 a.m., Eastern Standard Time, for
the purposes set forth in the Notice of Meeting and this Proxy Statement. Our
principal executive offices are located at 220 South Orange Avenue, Livingston
Corporate Park, Livingston, New Jersey 07039. The approximate date on which this
statement and the accompanying proxy will be mailed to stockholders is November
10, 2003.

                          THE VOTING AND VOTE REQUIRED

      On the record date for the meeting, November 7, 2003, there were
outstanding [18,226,732] shares of our common stock, par value $.001 per share
(the "Common Stock"), each of which will be entitled to one vote and 25,365
shares of Series A Preferred Stock, each entitled to one vote per each share of
Common Stock into which it is convertible. Each Series A Share is presently
convertible into 13,142 shares of Common Stock. The Series A Shares and the
shares of Common Stock vote together as one class.

      Approval of the proposed amendment to our Certificate of Incorporation to
effect a reverse stock split of the Common Stock will require the affirmative
vote of a majority of all outstanding shares of Common Stock entitled to vote on
this proposal.

      All shares represented by valid Proxies will be voted in accordance with
the instructions contained therein. In the absence of instructions, Proxies will
be voted FOR each of the stated matters being voted on at the meeting. A Proxy
may be revoked by the stockholder giving the Proxy at any time before it is
voted, either by oral or written notice, and a prior Proxy is automatically
revoked by a stockholder giving a subsequent Proxy or attending and voting at
the meeting. Attendance at the meeting, however, in and of itself does not
revoke a prior Proxy. Shares represented by Proxies marked "ABSTAIN" on any
other proposal will not be counted in determining whether the requisite vote has
been received for such proposal. In instances where brokers are prohibited from
exercising discretionary authority for beneficial owners who have not returned
Proxies ("broker non-votes"), those shares will not be included in the vote
totals. Accordingly, a high number of abstentions and broker non-votes may
negatively effect our ability to obtain approval of a proposal when approval
requires an affirmative vote of a majority of all outstanding shares of Common
Stock entitled to vote.


                                       1


APPROVAL OF AN AMENDMENT TO MILESTONE'S CERTIFICATE OF INCORPORATION TO EFFECT A
 REVERSE STOCK SPLIT OF ITS COMMON STOCK AT A RATIO NO GREATER THAN ONE-FOR-TEN
 AT ANY TIME PRIOR TO DECEMBER 31, 2004, AT THE SOLE DISCRETION OF MILESTONE'S
   BOARD OF DIRECTORS, IN CONNECTION WITH AN UNDERWRITTEN PUBLIC OFFERING BY
                                   MILESTONE

General

      On October 8, 2003, our Board of Directors (the "Board") unanimously
adopted a resolution, subject to stockholder approval, to amend our Certificate
of Incorporation to effect a reverse split of the Common Stock. The ratio of the
reverse stock split that the Board approved and deemed advisable and for which
it is seeking stockholder approval would not be greater than one new share for
ten old shares. The Board, in its sole discretion, will determine the exact
ratio of the reverse stock split, after taking into account the considerations
described below. The Board would also have the discretion not to take any
action.

      We would implement the reverse stock split only in connection with an
underwritten public offering by us described below (the "Offering"). The Board
will determine the exact ratio of the reverse stock split based on the advice of
the underwriter of the Offering (the "Underwriter"). The Board's decision will
take into account the impact of price on the Underwriter's ability to market the
securities to be sold in the Offering and the possibility of price erosion in
the interval between the date the split is implemented and the effective date of
the Offering as well as any other factors it deems relevant. If the Board
determines that it is advantageous to implement a reverse stock split, it would
do so approximately two weeks before the effective date of the Offering.
However, implementation of the split does not guarantee that the Offering will
occur.

      If our stockholders approve the reverse stock split proposal and the Board
decides to implement the reverse stock split, we will file a Certificate of
Amendment (as described below) with the Secretary of State of the State of
Delaware to effect the reverse split of the shares of Common Stock then issued
and outstanding at the specific ratio determined by the Board. The reverse stock
split, if implemented, would not change the number of authorized shares or the
par value of Common Stock. Except for any changes as a result of the treatment
of fractional shares, each stockholder will hold the same percentage of Common
Stock outstanding immediately prior to the reverse stock split as such
stockholder did immediately prior to the reverse split.

Reasons For This Proposal

      The principal purpose of the reverse stock split is to facilitate the
Offering, which, we believe, is necessary to maintain our listing on the
American Stock Exchange (the "AMEX"). In order to maintain that listing, we
must, among other requirements, maintain stockholders' equity of at least $6
million.

      On May 2, 2002, we received a letter from the AMEX advising us that we
have fallen below the stockholders' equity criterion and requesting that we
submit a recovery plan detailing any actions we have taken, or planned to take
within the next 18 months to bring us into compliance. On June 10, 2002, and as
supplemented on August 14, 2002, we submitted a detailed recovery plan to the
AMEX demonstrating how we expect to meet this requirement. On August 23, 2002,
the AMEX advised us that they had determined that the plan makes a reasonable
demonstration of our ability to regain compliance with the continued listing
standards by December 31, 2003. The plan submitted to AMEX contemplates a public
offering of equity securities before the end of 2003.


                                       2


      The proposed Offering is the type of offering contemplated by the plan.
The Underwriter had advised us that the Offering is more likely to succeed if
the market price of a share of our Common Stock is in the range of $4.00 to
$5.00. On October 30, 2003, the market price of a share of our Common Stock was
$2.38. However, before our stock price began its recent rise, it has been as low
as $.14. If the price continues to rise, it may not be necessary to implement
the reverse stock split. On the other hand, if the price of a share of our
Common Stock remains at its current level or begins to fall, it is likely that
we would have to implement a reverse stock split to facilitate the Offering.

      We believe that maintaining our listing on AMEX is in both our and our
stockholders' best interests. First, we believe that prospective investors will
view an investment in us more favorably if our stock is listed on AMEX as
opposed to the over-the-counter market. This will enhance our access to capital
and increase our flexibility in responding to anticipated capital requirements.
Second, we believe that the current per share price level of the Common Stock
has reduced the effective marketability of the Common Stock because of the
reluctance of many leading brokerage firms to maintain active analyst coverage
of low-priced stocks, to recommend low-priced stocks to their clients or to even
deal in low price stocks. In addition, since brokerage commissions on low-priced
stock may represent a higher percentage of the stock price than commissions on
higher-priced stock, the current share price of the Common Stock can result in
individual stockholders paying transaction costs (commission, markups or
markdowns) that represent a higher percentage of their total share value than
would be the case if the share price were substantially higher. Also, some
investors may view low-priced stock as speculative and unattractive, although
some other investors may be attracted to low-priced stock because of the greater
trading volatility sometimes associated with such securities. Such a limited
shareholder base may have the undesirable effect of artificially limiting demand
for the Common Stock, thus depressing the stock price. For all of the above
reasons, the Board believes that the reverse stock split is in both of our and
our stockholders' best interests.

      Since it is not absolutely certain at this time that a reverse split will
be necessary or, if necessary, what the ratio should be, the Board believes that
it should have maximum flexibility to determine the timing and the exact ratio
of the reverse stock split. This will allow the Board to move expeditiously if
and when the Underwriter advises the Board that the Offering should be launched.
If the Board does not have that flexibility, it will result in a delay and
possible loss of market opportunity.

      As discussed, the reverse stock split will only be implemented if the
Board determines that the reverse stock split is in both the best interests of
the Company and its stockholders. In connection with any determination to effect
a reverse stock split, the Board will set the timing for such a split and select
the specific ratio of the reverse stock split. These determinations will be made
by the Board to create the greatest marketability of our Common Stock based on
prevailing market conditions at that time. No further action on the part of
stockholders will be required to either implement or abandon the reverse stock
split. If the Board does not implement a reverse stock split prior to December
31, 2004, the authority granted in this proposal to implement a reverse stock
split on these terms will expire. The Board reserves its right to elect not to
proceed with the reverse stock split if it determines, in its sole discretion,
that the split is no longer in our best interests and those of our stockholders.

The Offering

      On [November __, 2003], we filed with the Securities Exchange Commission a
registration statement on Form S-2 (the "Registration Statement"). The
Registration Statement covers the sale of [____________] units ([___________]
units if the underwriter exercises the over-allotment option in full), each unit
consisting of two shares of Common Stock and one warrant to purchase one share
of Common Stock at an exercise price equal to 75% of the unit offering price
(each a "Unit" and collectively, the "Units"). The warrants included in the
units (the "Warrants") are exercisable at any time after they become separately
tradable until their


                                       3


expiration date, five years after the date of the closing of the Offering. Some
or all of the Warrants may be redeemed by us at a price of $0.01 per Warrant, by
giving not less than 30 days notice to the holders of the Warrants, which we may
do at any time after the closing price for our Common Stock on the principal
exchange on which it trades (i.e., AMEX) has equaled or exceeded 100% of the
Unit offering price. The Common Stock included in the Units and the Warrants
will trade only as a Unit for 30 days following the closing date of the
Offering, unless the underwriter determines that separate trading should occur
earlier. After that date, the Common Stock included in the Units and the
Warrants will trade separately. The size of the Offering, the number of Units to
be sold, the price per Unit, the securities included in the Units and the
exercise price of the Warrants are all subject to change.

      As currently contemplated, the gross proceeds from the Offering are
expected to be [$ _____] and the net proceeds, after taking into account
underwriting discounts and commissions and estimated offering expenses, is
expected to be [$_______.] As set forth in the Registration Statement, we will
use the net proceeds of the Offering to repay indebtedness, including
indebtedness to an affiliate, to contract-manufacture equipment used in our
business and for other capital expenditures, to pay sales and marketing and
personnel expenses, to increase our inventory and for miscellaneous working
capital. We will retain broad discretion in the allocation of the net proceeds
within the categories set forth above. The amounts actually expended within
these categories may vary significantly and will depend on a number of factors,
including our rate of revenue growth, cash generated by operations, evolving
business needs and the other factors.

Principal Effects of the Reverse Stock Split

      In general, a reverse stock split combines the outstanding shares of
Common Stock into a fewer number of shares. A share of Common Stock outstanding
after giving effect to the reverse stock split should trade at a higher price
per share than a share of Common Stock outstanding before giving effect to the
reverse stock split. However, we cannot assure that there will not be price
erosion after the reverse stock split is implemented. If that happens, the value
of your holdings will decrease.

      Corporate Matters. If approved and effected, the reverse stock split would
have the following effects:

            o     depending on the exact reverse stock split ratio selected by
                  the Board, up to ten shares of Common Stock outstanding before
                  the reverse stock split ("Old Shares") owned by a stockholder
                  would be exchanged for one share of Common Stock after the
                  reverse stock split ("New Shares");

            o     the number of shares of Common Stock issued and outstanding
                  will be reduced proportionately based on the reverse stock
                  split ratio selected by the Board;

            o     based on the reverse stock split ratio selected by the Board,
                  proportionate adjustments will be made to the per share
                  exercise price and the number of shares issuable upon the
                  exercise of all outstanding options and warrants entitling the
                  holders thereof to purchase shares of Common Stock, which will
                  result in approximately the same aggregate price being
                  required to be paid for such options or warrants upon exercise
                  of such options or warrants immediately preceding the reverse
                  stock split;

            o     the number of shares reserved for issuance under our existing
                  stock option plan will be reduced proportionately based on the
                  reverse stock split ratio selected by the Board.

            o     The number of Old Shares into which our Series A Shares are
                  convertible would be proportionately adjusted into an
                  equivalent number of New Shares.


                                       4


      If approved and effected, the reverse stock split will be effected
simultaneously for all Common Stock and the ratio will be the same for all
Common Stock. The reverse stock split will affect all of our stockholders
uniformly and will not affect any stockholder's percentage ownership interests
in us, except to the extent that the reverse stock split results in any of our
stockholders owning a fractional share. As described below, stockholders holding
fractional shares will be entitled to cash payments in lieu of such fractional
shares. The cash payments will reduce the number of post-split stockholders to
the extent there are stockholders presently holding fewer than up to ten shares,
depending on the ratio for the reverse stock split selected by the Board. This,
however, is not the purpose for which we are effecting the reverse stock split.
Common Stock issued pursuant to the reverse stock split will remain fully paid
and non-assessable. We will continue to be subject to the periodic reporting
requirements of the Securities Exchange Act of 1934, as amended.

      Capitalization. As of November 7, 2003 we had [18,226,732] shares issued
and outstanding. The chart below sets forth the number of shares that will be
issued and outstanding assuming the reverse stock split is effected at various
ratios.

              Ratio                   Number of Shares Issued and Outstanding
------------------------------     ---------------------------------------------

         one-for-two                                9,113,366
         one-for-three                              6,075,577
         one-for-four                               4,556,683
         one-for-five                               3,645,346
         one-for-six                                3,037,788
         one-for-seven                              2,603,818
         one-for-eight                              2,278,341
         one-for-nine                               2,025,192
         one-for-ten                                1,822,673

      Fractional Shares. No scrip or fractional certificates will be issued in
connection with the reverse stock split. Stockholders who otherwise would be
entitled to receive fractional shares because they hold a number of Old Shares
not evenly divisible by the number selected by the Board for the reverse stock
split ratio will be entitled, upon surrender of certificate(s) representing such
shares, to a cash payment in lieu thereof. The cash payment will equal the
product obtained by multiplying (a) the fraction to which the stockholder would
otherwise be entitled by (b) the market price per New Share at the time of
payment. On behalf of the holders who would otherwise be entitled to receive a
fractional share our transfer agent will aggregate all fractional shares and
sell them, at the then prevailing prices on the open market, as soon as
practicable after the effective time of the reverse stock split.

      The ownership of a fractional interest will not give the holder thereof
any voting, dividend or other rights except to receive payment therefor as
described herein.

      Stockholders should be aware that, under the escheat laws of the various
jurisdictions where they reside, where we are domiciled and where the funds will
be deposited, sums due for fractional interests that are not timely claimed
after the effective time may be required to be paid to the designated agent for
each such jurisdiction. Thereafter, stockholders otherwise entitled to receive
such funds may have to seek to obtain them directly from the state to which they
were paid.

      If approved and effected, the reverse stock split will result in some
stockholders owning "odd lots" of less than 100 shares of Common Stock.
Brokerage commissions and other costs of transactions in odd lots are generally
somewhat higher than the costs of transactions in "round lots" of even multiples
of 100 shares.


                                       5


      Authorized Shares. The reverse stock split would affect all issued and
outstanding shares of Common Stock and outstanding rights to acquire Common
Stock. Upon the effectiveness of the reverse stock split, the number of
authorized shares of Common Stock available for issuance would increase due to
the reduction in the number of shares of Common Stock issued and outstanding
based on the reverse stock split ratio selected by the Board. As of October 31,
2003, we had 50,000,000 shares of Common Stock authorized and 18,162,193 shares
of Common Stock issued and outstanding. Authorized but unissued shares will be
available for issuance, and we may issue such shares in the future. If we issue
additional shares, the ownership interest of holders of Common Stock will be
diluted.

      Accounting Matters. The reverse stock split will not affect the par value
of Common Stock. As a result, as of the effective time of the reverse stock
split, the stated capital on our balance sheet attributable to Common Stock will
be reduced proportionately based on the reverse stock split ratio selected by
the Board, and the additional paid-in capital account will be credited with the
amount by which the stated capital is reduced. The per share net income or loss
and net book value of Common Stock will be restated because there will be fewer
shares of Common Stock outstanding.

      Potential Anti-Takeover Effect. Although the increased proportion of
unissued authorized shares to issued shares could, under certain circumstances,
have an anti-takeover effect (for example, by permitting issuances that would
dilute the stock ownership of a person seeking to effect a change in the
composition of the Board or contemplating a tender offer or other transaction
for the combination of Milestone with another company), the reverse stock split
proposal is not being proposed in response to any effort of which we are aware
to accumulate our shares of Common Stock or obtain control of us, nor is it part
of a plan by management to recommend a series of similar amendments to the Board
and stockholders. Other than the reverse stock split proposal, the Board does
not currently contemplate recommending the adoption of any other amendments to
our Certificate of Incorporation that could be construed to affect the ability
of third parties to take over or change the control of us.

Procedure for Effecting Reverse Stock Split and Exchange of Stock Certificates

      If the stockholders approve the proposed amendment and the Board decides
to implement the reverse stock split on or prior to December 31, 2004, we will
file a Certificate of Amendment (the "Amendment") with the Secretary of State of
the State of Delaware to amend its existing Certificate of Incorporation. The
reverse stock split will become effective at the time specified in the
Amendment, which is referred to below as the "effective time." Beginning at the
effective time, each certificate representing Old Shares will be deemed for all
corporate purposes to evidence ownership of New Shares. The text of the
Amendment to effect the reverse stock split, if implemented by the Board, would
be in substantially the form attached hereto as Appendix I; provided, however,
that the text of the form of Amendment attached hereto is subject to
modification to include changes that may be required by the office of the
Secretary of State of the State of Delaware and as the Board deems necessary and
advisable to effect the reverse stock split, including the insertion of the
effective time and the applicable reverse stock split ratio determined by the
Board.

      As soon as practicable after the effective time, stockholders will be
notified that the reverse stock split has been effected. We expect that our
transfer agent will act as exchange agent for purposes of implementing the
exchange of stock certificates. Holders of Old Shares will be asked to surrender
to the exchange agent certificates representing Old Shares in exchange for
certificates representing New Shares in accordance with the procedures to be set
forth in the letter of transmittal we send to our stockholders. No new
certificates will be issued to a stockholder until such stockholder has
surrendered such stockholder's outstanding certificate(s), together with the
properly completed and executed letter of transmittal, to the exchange agent.
Any Old Shares submitted for transfer, whether pursuant to a sale, other
disposition or otherwise, will


                                       6


automatically be exchanged for New Shares. STOCKHOLDERS SHOULD NOT DESTROY ANY
STOCK CERTIFICATE(S) AND SHOULD NOT SUBMIT ANY CERTIFICATE(S) UNTIL REQUESTED TO
DO SO.

No Dissenters' Rights

      Under the Delaware General Corporation Law, our stockholders are not
entitled to dissenters' rights with respect to the reverse stock split, and we
will not independently provide stockholders with any such right.

Federal Income Tax Consequences of the Reverse Stock Split

      The following is a summary of certain material federal income tax
consequences of the reverse stock split, does not purport to be a complete
discussion of all of the possible federal income tax consequences of the reverse
stock split and is included for general information only. Further, it does not
address any state, local or foreign income or other tax consequences. Also, it
does not address the tax consequences to holders that are subject to special tax
rules, such as banks, insurance companies, regulated investment companies,
personal holding companies, foreign entities, nonresident alien individuals,
broker-dealers and tax-exempt entities. The discussion is based on the
provisions of the United States federal income tax law as of the date hereof,
which is subject to change retroactively as well as prospectively. This summary
also assumes that the Old Shares were, and the New Shares will be, held as a
"capital asset," as defined in the Internal Revenue Code of 1986, as amended
(i.e., generally, property held for investment). The tax treatment of a
stockholder may vary depending upon the particular facts and circumstances of
such stockholder. Each stockholder is urged to consult with his or her own tax
advisor with respect to the tax consequences of the reverse stock split.

      Other than the cash payments for fractional shares discussed below, no
gain or loss should be recognized by a stockholder upon such stockholder's
exchange of Old Shares for New Shares pursuant to the reverse stock split. The
aggregate tax basis of the New Shares received in the reverse stock split
(including any fraction of a New Share deemed to have been received) will be the
same as the stockholder's aggregate tax basis in the Old Shares exchanged. In
general, stockholders who receive cash in exchange for their fractional share
interests in the New Shares as a result of the reverse stock split will
recognize gain or loss based on their adjusted basis in the fractional share
interests redeemed. The stockholder's holding period for the New Shares will
include the period during which the stockholder held the Old Shares surrendered
in the reverse stock split.

      Our view regarding the tax consequences of the reverse stock split is not
binding on the Internal Revenue Service or the courts. ACCORDINGLY, EACH
STOCKHOLDER SHOULD CONSULT WITH HIS OR HER OWN TAX ADVISOR WITH RESPECT TO ALL
OF THE POTENTIAL TAX CONSEQUENCES TO HIM OR HER OF THE REVERSE STOCK SPLIT.

             THE BOARD UNANIMOUSLY RECOMMENDS A VOTE FOR APPROVAL OF
                            THE REVERSE STOCK SPLIT.


                                       7


               SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND
                                   MANAGEMENT

      The following table sets forth information regarding the beneficial
ownership of our common shares as of the date of this prospectus by:

o     each person, or group of affiliated persons, known by us to be the
      beneficial owner of more than 5% of our outstanding common shares;

o     each of our directors;

o     each executive officer named in the summary compensation table above; and

o     all of our directors and executive officers as a group.

      The following table does not take into account any common shares sold as a
result of the exercise of the over-allotment option granted to the underwriters.
Except as otherwise indicated, the persons listed below have sole voting and
investment power with respect to all of the common shares owned by them. The
individual shareholders have furnished all information concerning their
respective beneficial ownership to us.



                                                          Shares of
                                                         Common Stock
                                                         Beneficially     Percentage of
         Name of Beneficial Owner (1)                     Owned (2)        Ownership
         ------------------------------------------------------------------------------
         Executive Officers and Directors
                                                                         
         Leonard Osser..............................      3,970,174(3)         20.98%
         Stuart J. Wildhorn.........................         40,333(4)             *
         Thomas M. Stuckey..........................         62,967(5)             *
         Paul Gregory...............................         32,422(6)             *
         Leonard M. Schiller........................         32,572(7)             *
         Jeffrey Fuller.............................         20,000(8)             *
         Leslie Bernhard............................         20,000(9)             *
         All Directors & Officers as a group........      4,178,468(10)        21.84%


----------
o     Less than 1%

      5% and Greater Stockholders

      K. Tucker Andersen
          c/o Cumberland Associates LLC
          1114 Avenue of the Americas
          New York, New York 10036            3,950,152(11)           21.67%

      Cumberland Associates, LLC
          1114 Avenue of the Americas
          New York, New York 10036            1,980,773(12)           10.87%

      Gintel Asset Management, Inc.
          6 Greenwich Office Park
          Greenwich, CT 06831                 1,347,000(13)            7.39%

(1)   The addresses of the persons named in this table are as follows: Leonard
      A. Osser, Stuart Wildhorn and Thomas M. Stuckey are all at 220 South
      Orange Avenue, Livingston Corporate Park, Livingston, NJ 07039., Paul
      Gregory, Innovative Programs Associates Inc., 370 E. 76th Street, New
      York, New York 10021; Leonard M. Schiller, Schiller, Klein & McElroy,
      P.C., 33 North Dearborn Street, Suite 1030, Chicago, Illinois 60602,
      Jeffrey Fuller, Eagle Chase, Woodbury, NY 11797 and Leslie Bernhard,
      AdStar, Inc., 4553 Glencoe Avenue, Suite 325, Marina del Rey, California
      90292.


                                       8


(2)   A person is deemed to be a beneficial owner of securities that can be
      acquired by such person within 60 days from the filing of this proxy
      statement upon the exercise of options and warrants or conversion of
      convertible securities. Each beneficial owner's percentage ownership is
      determined by assuming that options, warrants and convertible securities
      that are held by such person (but not held by any other person) and that
      are exercisable or convertible within 60 days from the filing of this
      report have been exercise or converted. Except as otherwise indicated, and
      subject to applicable community property and similar laws, each of the
      persons named has sole voting and investment power with respect to the
      shares shown as beneficially owned. All percentages are determined based
      on the number of all shares, including those underlying options
      exercisable within 60 days from the filing of this proxy statement held by
      the named individual, divided by [18,226,732] outstanding shares on
      November 7, 2003 and those shares underlying options exercisable within
      60 days from the filing of this proxy statement, held by the named
      individual.

(3)   Includes (i) 614,183 shares issuable upon exercise of stock options within
      60 days of the date hereof, which until January 31 are exercisable at
      $1.00,and beginning February 1, 2004 will be exercisable at $2.00, (ii)
      warrants immediately exercisable to purchase 35,714 shares at $1.75 per
      share and (iii) option for 50,000 shares exercisable at $1.00 per share
      within 60 days .

(4)   Includes 33,333 shares subject to stock options, exercisable within 60
      days of the date hereof at $2.50 per share and 7,000 shares subject to
      stock options, exercisable within 60 days of the date hereof at $.75 per
      share.

(5)   Includes 21,000 shares subject to stock options, exercisable within 60
      days of the date hereof at $3.00 per share and 25,000 shares subject to
      stock options, exercisable within 60 days of the date hereof at $2.1875
      per share, 6,667 shares subject to stock options exercisable within 60
      days of the date hereof at $2.50 per share and 7,000 shares subject to
      stock options exercisable within 60 days of the date hereof at $.75 per
      share. Mr. Stuckey disclaims beneficial ownership of (i) 10,000 shares,
      which are held by his wife as custodian for their children, and (ii) 1,700
      shares which are owned by his wife in her IRA.

(6)   Includes 150 shares held by Mr. Gregory's wife, 12,422 shares subject to
      stock options, exercisable within 60 days of the date hereof at $2.1875
      per share and 20,000 subject to stock options, exercisable within 60 days
      of the date hereof at $.50 per share.

(7)   Includes 12,422 shares subject to stock options, exercisable within 60
      days of the date hereof at $2.1875 per share and 20,000 subject to stock
      options, exercisable within 60 days of the date hereof at $.50 per share.

(8)   Includes 20,000 shares subject to stock options, exercisable within 60
      days of the date hereof at $.50 per share.

(9)   Includes 20,000 shares subject to stock options, exercisable within 60
      days of the date hereof at $.50 per share

(10)  Includes 734,361 shares subject to stock options, 35,714 shares subject to
      warrants all of which are exercisable within sixty (60) days of the date
      hereof and 92,000 shares to which he has shared voting and dispositive
      power.

(11)  Based solely upon an amendment to Schedule 13D filed by K. Tucker Andersen
      with the Securities and Exchange Commission on ___________, 2003.

(12)  Based solely upon an amendment to Schedule 13G filed by Cumberland
      Associates, LLC with the Securities and Exchange Commission on
      _____________, 2003.

(13)  Includes 555,000 shares held by Gintel Asset Management and 792,000 shares
      held by Robert Gintel Florida Intangible Tax Trust. Excludes 110,000
      shares owned by Barbara Gintel (Robert Gintel's spouse) and 150,000 shares
      owned by Gintel Partners Fund.

      All of the common shares set forth in the above table are covered by
lock-up agreements prohibiting their sale, assignment or transfer for 90 days
following the date of this prospectus without the prior written consent of the
representative.


                                       9


                 Certain Relationships and Related Transactions

              CERTAIN RELATIONSHIPS AND RELATED PARTY TRANSACTIONS

      In April 2000, Mr. Osser provided Milestone with a $200,000 line of credit
which is payable on January 2, 2003. In December 2001, the Company reached an
agreement with Mr. Osser to satisfy $491,346 of his deferred compensation
through the issuance of 614,183 units, each unit consisted of one share of
Milestone common stock and one warrant to purchase an additional share of each
stock. These units were issued to Mr. Osser in January 2002.

      On October 2, 2003, Milestone issued to Mr. Osser 400,454 shares of common
stock in repayment of 6%/12% notes in the aggregate principal and interest
amount of $404,638.

      On October 9, 2003 we reached an agreement to satisfy $448,356 of debt and
accrued interest and $336,000 of deferred compensation due to Mr. Osser, through
the issuance of units, similar to the units offered in this offering, on the
later of January 2, 2004 or the effective date of this offering. The units will
be issued at the same price as offered in this offering.

      We have adopted a policy that, in the future, the audit committee must
review all transactions with any officer, director or 5% shareholder.

             Section 16(a) Beneficial Ownership Reporting Compliance

      Section 16(a) of the Securities Exchange Act of 1934 requires our officers
and directors, and persons who own more than ten percent (10%) of a registered
class of our equity securities to file reports of ownership and changes in
ownership with the Securities and Exchange Commission ("SEC"). Officers,
directors and greater than ten percent (10%) stockholders are required by SEC
regulations to furnish the Company with copies of all Section 16(a) forms they
file.

      To the best of our knowledge, based solely on review of the copies of such
forms furnished to us, or written representations that no other forms were
required, we believe that all Section 16(a) filing requirements applicable to
its officers, directors and greater than ten percent (10%) shareholders were
complied with during 2002.


                                       10


                                  MISCELLANEOUS

Other Matters

      We know of no matter other than the foregoing to be brought before the
Special Meeting of Stockholders, but if such other matters properly come before
the meeting, or any adjournment thereof, the persons named in the accompanying
form of Proxy will vote such Proxy on such matters in accordance with their best
judgment.

Reports and Financial Statements

      The following information is hereby incorporated by reference and is
deemed part of this proxy statement:

      (i)   The audited financial statements from our Annual Report to
            Stockholders for the fiscal year ended December 31, 2002; and

      (ii)  The unaudited financial statements and the information set forth
            under the caption "Management's Discussion and Analysis of Financial
            Condition and Results of Operations"; from our quarterly report on
            form 10-QSB for the fiscal quarter ended September 30, 2003.

      Upon written or oral request, we will provide, without charge, each person
to whom a copy of this proxy statement is delivered, a copy of any document
incorporated by reference in this proxy statement (other than exhibits, unless
such exhibits are specifically incorporated by reference in such documents).
Requests should be directed to Milestone Scientific Inc., 220 South Orange
Avenue, Livingston Corporate Park, Livingston, New Jersey 07039, (973) 535-2717
Attention: Thomas Stuckey, Chief Financial Officer.

Solicitation of Proxies

      We will beat the entire cost of the solicitation of proxies. Proxies may
be solicited by telephone, telegraph, mail or personal interview, by our
directors, officers and regular employees, without extra compensation.
Solicitation is not to be made by specifically engaged employees or paid
solicitors. We will also reimburse brokerage houses and other custodians,
nominees and fiduciaries for their reasonable expenses for sending proxies and
proxy material to the beneficial owners of its Common Stock.

Stockholder Proposals

      Stockholder proposals intended to be presented at our 2004 Annual Meeting,
must be received by us no later than March 1, 2004 in order to be included in
our proxy statement related to that meeting. Such proposals should be addressed
to Thomas M. Stuckey, Chief Financial Officer, Milestone Scientific Inc., 220
South Orange Avenue, Livingston Corporate Park, Livingston, New Jersey 07039.

Accounting Matters

      J.H. Cohn LLP served as our independent accountants for the year ended
December 31, 2002. Representatives of J.H. Cohn LLP are expected to be present
at the Special Meeting with an opportunity to make a statement if they desire to
do so, and will be available to respond to appropriate questions. The J.H. Cohn
LLP report included in this Proxy Statement relates to our historical financial
information for the year ended December 31, 2002.


                                       11


             EVERY STOCKHOLDER, WHETHER OR NOT HE OR SHE EXPECTS TO
            ATTEND THE ANNUAL MEETING IN PERSON, IS URGED TO EXECUTE
           THE PROXY AND RETURN IT PROMPTLY IN THE ENCLOSED BUSINESS
                                REPLY ENVELOPE.

                                          By order of the Board of Directors


                                          Leonard Osser
                                          Chairman of the Board

Livingston, New Jersey
November __, 2003


                                       12


                                   APPENDIX I

                           CERTIFICATE OF AMENDMENT OF

                        THE CERTIFICATE OF INCORPORATION

                                       OF

                           MILESTONE SCIENTIFIC, INC.

        (Pursuant to Section 242 of the Delaware General Corporation Law)

                                   ----------

      It is hereby certified that:

      1.    The name of the corporation is Milestone Scientific Inc (the
            "Corporation").

      2.    The Certificate of Incorporation of the Corporation was filed by the
            Department of State on August 17, 1989 (under the name "U.S.
            Opportunity Search, Inc.") and subsequent amendments thereto were
            filed on July 13, 1995, December 6, 1996 and, December 17, 1997.

      3.    The Certificate of Incorporation of the Corporation is hereby
            amended to effect a reverse split of the Corporation's issued and
            outstanding shares of common stock, without changing the par value
            per share.

      4.    To accomplish the foregoing amendment, Article FOURTH of the
            Certificate of Incorporation is amended to include the following:

                  "Upon this Certificate of Amendment of the Certificate of
                  Incorporation of the Corporation becoming effective pursuant
                  to the Delaware General Corporation Law (the "Effective
                  Time"), every [in the range of two (2) to ten (10) to be
                  determined by the Board] shares of the Corporation's common
                  stock, par value $.001 per share (the "Old Common Stock"),
                  issued and outstanding immediately prior to the Effective
                  Time, will be automatically converted into one share of common
                  stock, par value $.001 per share, of the Corporation (the "New
                  Common Stock").

                  Notwithstanding the immediately preceding sentence, no
                  fractional shares of New Common Stock shall be issued to the
                  holders of record of Old Common Stock in connection with the
                  foregoing reverse split of shares of Old Common Stock. In lieu
                  thereof, the aggregate of all fractional shares otherwise
                  issuable to the holders of record of Old Common Stock shall be
                  issued to the Corporation's transfer agent, as agent for, the
                  accounts of all holders of record of Old Common Stock
                  otherwise entitled to have a fraction of a share issued to
                  them. The sale of all of the fractional interests will be
                  effected by the transfer agent as soon as practicable after
                  the Effective Time on the basis of prevailing market prices of
                  the New Common Stock at the time of sale. After such sale and
                  upon the surrender of the stockholders' stock certificates,
                  the



                  transfer agent will pay to such holders of record their pro
                  rata share of the net proceeds derived from the sale of the
                  fractional interests.

                  Each stock certificate that, immediately prior to the
                  Effective Time, represented shares of Old Common Stock shall,
                  from and after the Effective Time, automatically and without
                  the necessity of presenting the same for exchange, represent
                  that number of whole shares of New Common Stock into which the
                  shares of Old Common Stock represented by such certificate
                  shall have been convertible (as well as the right to receive
                  cash in lieu of any factional shares of New Common Stock as
                  set forth above), provided, however, that each holder of
                  record of a certificate that represented shares of Old Common
                  Stock shall receive, upon surrender of such certificate, a new
                  certificate representing the number of whole shares of New
                  Common Stock into which the shares of Old Common Stock
                  represented by such certificate shall have been convertible,
                  as well as any cash in lieu of fractional shares of New Common
                  Stock to which such holder may be entitled pursuant to the
                  immediately preceding paragraph."

      5.    The Amendment herein certified have been duly adopted in accordance
            with the provisions of Section 242 of the Delaware General
            Corporation Law.

      6.    This Certificate of Amendment shall become effective upon the filing
            hereof in the Office of the Secretary of State of the State of
            Delaware.

Executed on this   day of ________ 2003


                                        _______________________________
                                        Name:
                                        Title:



                           APPENDIX II (FORM OF PROXY)

                            MILESTONE SCIENTIFIC INC.
                                    P R O X Y
                     FOR SPECIAL MEETING OF THE STOCKHOLDERS
                                DECEMBER 9, 2003
           THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS

      The undersigned hereby appoints Leonard Osser and Thomas M. Stuckey, and
each of them, with full power of substitution, as proxies to vote the shares
which the undersigned is entitled to vote at the Special Meeting of the
Stockholders of Milestone Scientific Inc. ("Company") to be held at the offices
of Morse, Zelnick, Rose & Lander, LLP, 405 Park Avenue, Suite 1401, New York,
New York 10022, on Tuesday, December 9, 2003 at 9:00 a.m., Eastern Standard Time
and at any adjournments thereof, hereby revoking any proxies heretofore given,
to vote all shares of common stock of the Company held or owned by the
undersigned as indicated on the proposals as more fully set forth in the Proxy
Statement, and in their discretion upon such other matters as may come before
the meeting.

Please mark "X" your votes as indicated:

Approval of grant of discretionary authority to the Company's board of directors
to amend the Company's certificate of incorporation to effect a reverse stock
split of the Company's common stock at a ratio of not more than one-for-ten at
any time prior to December 31, 2004.

FOR |_| AGAINST |_| ABSTAIN |_|

                              (Continued, and to be signed, on the Reverse Side)
--------------------------------------------------------------------------------
                                    FOLD HERE

--------------------------------------------------------------------------------
THIS PROXY WHEN PROPERLY SIGNED WILL BE VOTED IN THE MANNER DIRECTED HEREIN BY
THE UNDERSIGNED SHAREHOLDER. IF NO DIRECTION IS MADE, THIS PROXY WILL BE VOTED
FOR THE PROPOSAL.

The undersigned hereby acknowledges receipt of the Notice of, and Proxy
Statement for, the aforesaid Special Meeting.

                                       Dated:                             , 2003


                                       _________________________________________
                                                 Signature of Stockholder


                                       _________________________________________
                                                 Signature of Stockholder

NOTE: When shares are held by joint tenants, both should sign. When signing as
attorney, executor, administrator, trustee, or guardian, please give full title
as such. If a corporation, please sign in full corporate name by President or
other authorized officer. If a partnership, please sign in partnership name by
an authorized person.

IMPORTANT - PLEASE FILL IN, SIGN AND RETURN PROMPTLY USING THE ENCLOSED
ENVELOPE.


                                       1