FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person * Almstead Neil Gregory   2. Issuer Name and Ticker or Trading Symbol PTC THERAPEUTICS, INC. [PTCT] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner __X__ Officer (give title below) _____ Other (specify below) EVP Research Pharma Ops & Tech (Last) (First) (Middle) C/O PTC THERAPEUTICS, INC., 100 CORPORATE COURT 3. Date of Earliest Transaction (Month/Day/Year) 09/27/2016 (Street) SOUTH PLAINFIELD, NJ 07080 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 09/27/2016   M   3,414 A $ 10.85 3,414 D   Common Stock 09/27/2016   M   6,586 A $ 10.85 10,000 D   Common Stock               1,295 I By spouse

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Underlying Securities (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Stock Option (Right to Buy)	$ 10.85	09/27/2016		M			3,414	(1)	05/15/2023	Common Stock	3,414	$ 10.85	66,898	D
Stock Option (Right to Buy)	$ 10.85	09/27/2016		M			6,586	(2)	05/15/2023	Common Stock	6,586	$ 10.85	3,102	D
Stock Option (Right to Buy)	$ 27.05							(3)	01/27/2024	Common Stock	40,000		40,000	D
Stock Option (Right to Buy)	$ 51							(4)	01/01/2025	Common Stock	69,550		69,550	D
Stock Option (Right to Buy)	$ 30.86							(5)	01/03/2026	Common Stock	55,000		55,000	D
Stock Option (Right to Buy)	$ 218.4							(7)	01/10/2022	Common Stock	166		166	D
Stock Option (Right to Buy)	$ 490.8							(7)	04/27/2021	Common Stock	216		216	D
Stock Option (Right to Buy)	$ 1,149.6							(7)	02/02/2020	Common Stock	200		200	D
Stock Option (Right to Buy)	$ 451.2							(7)	05/15/2019	Common Stock	200		200	D
Stock Option (Right to Buy)	$ 735.6							(7)	04/01/2018	Common Stock	194		194	D
Stock Option (Right to Buy)	$ 735.6							(7)	01/25/2018	Common Stock	166		166	D
Stock Option (Right to Buy)	$ 626.4							(7)	04/18/2017	Common Stock	137		137	D
Stock Option (Right to Buy)	$ 10.85							(7)	05/15/2023	Common Stock	600		600	I	By spouse
Stock Option (Right to Buy)	$ 27.05							(7)	01/27/2024	Common Stock	1,300		1,300	I	By spouse
Stock Option (Right to Buy)	$ 51							(7)	01/01/2025	Common Stock	2,060		2,060	I	By spouse
Restricted Stock Unit	(6)							(6)	(6)	Common Stock	750		750	I	By spouse
Stock Option (Right to Buy)	$ 218.4							(7)	01/10/2022	Common Stock	7		7	I	By spouse
Stock Option (Right to Buy)	$ 490.8							(7)	04/27/2021	Common Stock	7		7	I	By spouse
Stock Option (Right to Buy)	$ 1,149.6							(7)	02/02/2020	Common Stock	1		1	I	By spouse
Stock Option (Right to Buy)	$ 508.8							(7)	10/07/2019	Common Stock	12		12	I	By spouse

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Almstead Neil Gregory C/O PTC THERAPEUTICS, INC. 100 CORPORATE COURT SOUTH PLAINFIELD, NJ 07080			EVP Research Pharma Ops & Tech

Signatures

/s/ Colleen Diver Johnson, attorney-in-fact		09/27/2016
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	This option was granted on May 15, 2013 and vests over four years, with 25% of the shares underlying the option vested on May 15, 2014 and an additional 2.083% of the original number of shares underlying the option vesting monthly thereafter, beginning on June 15, 2014.
(2)	This option was granted on May 15, 2013 and vests over four years, with 25% of the shares underlying the option vested on December 31, 2013 and an additional 2.083% of the original number of shares underlying the option vesting monthly thereafter, beginning on January 31, 2014.
(3)	This option was granted on January 28, 2014, and vests over four years, with 25% of the shares underlying the option vesting on January 1, 2015, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on April 1, 2015.
(4)	This option was granted on January 2, 2015, and vests over four years, with 25% of the shares underlying the option vesting on January 1, 2016, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on April 1, 2016.
(5)	This option was granted on January 4, 2016, and vests over four years, with 25% of the shares underlying the option vesting on January 4, 2017, and an additional 6.25% of the original number of shares underlying the option vesting at the end of each successive three-month period thereafter, beginning on April 4, 2017.
(6)	This restricted stock unit (RSU) award was granted on January 4, 2016 and vests in equal installments over four years on each anniversary of the grant date. Upon vesting, each RSU will convert into one share of common stock of the Issuer.
(7)	Currently exercisable.

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