Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
Mehra Anand
  2. Issuer Name and Ticker or Trading Symbol
AERIE PHARMACEUTICALS INC [AERI]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
C/O SOFINNOVA VENTURES, 2800 SAND HILL ROAD, SUITE 150
3. Date of Earliest Transaction (Month/Day/Year)
05/22/2014
(Street)

MENLO PARK, CA 94025
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 05/22/2014   S   323,932 D $ 16 2,766,657 I See footnote (1)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
Mehra Anand
C/O SOFINNOVA VENTURES
2800 SAND HILL ROAD, SUITE 150
MENLO PARK, CA 94025
  X   X    
HEALY JAMES
C/O SOFINNOVA VENTURES
2800 SAND HILL ROAD, SUITE 150
MENLO PARK, CA 94025
    X    
POWELL MICHAEL
C/O SOFINNOVA VENTURES
2800 SAND HILL ROAD, SUITE 150
MENLO PARK, CA 94025
    X    
Buatois Eric
C/O SOFINNOVA VENTURES
2800 SAND HILL ROAD, SUITE 150
MENLO PARK, CA 94025
    X    
SOFINNOVA VENTURE PARTNERS VII L P
C/O SOFINNOVA VENTURES
2800 SAND HILL ROAD, SUITE 150
MENLO PARK, CA 94025
    X    
Sofinnova Management VII, L.L.C.
C/O SOFINNOVA VENTURES
2800 SAND HILL ROAD, SUITE 150
MENLO PARK, CA 94025
    X    

Signatures

 /s/ Nathalie Auber, Attorney-in-Fact for Anand Mehra   05/23/2014
**Signature of Reporting Person Date

 /s/ Nathalie Auber, Attorney-in-Fact for James Healy   05/23/2014
**Signature of Reporting Person Date

 /s/ Nathalie Auber, Attorney-in-Fact for Eric Buatois   05/23/2014
**Signature of Reporting Person Date

 /s/ Nathalie Auber, Attorney-in-Fact for Michael Powell   05/23/2014
**Signature of Reporting Person Date

 /s/ Nathalie Auber, Attorney-in-Fact for Sofinnova Venture Partners VII, L.P.   05/23/2014
**Signature of Reporting Person Date

 /s/ Nathalie Auber, Attorney-in-Fact for Sofinnova Management VII, L.L.C.   05/23/2014
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The securities are owned directly by Sofinnova Venture Partners VII, L.P. ("SV VII"). Sofinnova Management VII, L.L.C. ("SV VII LLC"), the general partner of SV VII, James Healy, Michael Powell, and Eric Buatois, the managing members of SV VII LLC, and Anand Mehra, a director of the Issuer, may be deemed to have shared voting and dispositive power over the shares owned by SV VII. Such persons and entities disclaim beneficial ownership over the shares owned by SV VII except to the extent of any pecuniary interest therein.

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