UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 ------------ FORM 6-K ------------ REPORT OF FOREIGN ISSUER Pursuant to Rule 13a-16 or 15d-16 of the Securities Exchange Act of 1934 DECEMBER 7, 2007 ------------ NOVO NORDISK A/S (Exact name of Registrant as specified in its charter) NOVO ALLE DK-2880, BAGSVAERD DENMARK (Address of principal executive offices) ------------ Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F Form 20-F [X] Form 40-F [ ] Indicate by check mark whether the registrant by furnishing the information contained in this Form is also thereby furnishing the information to the Commission pursuant to Rule 12g3-2(b) under the Securities Exchange Act of 1934. Yes [ ] No [X] If "Yes" is marked, indicate below the file number assigned to the registrant in connection with Rule 12g-32(b):82-_____________________ HOLDING(S) IN COMPANY MAJOR SHAREHOLDER NOTIFICATION In accordance with Section 29 of the Securities Trading Act, Novo Nordisk hereby reports that Capital Group Companies on 4 December 2007 informed Novo Nordisk that Capital Group Companies now holds 93,507,562 B shares of DKK 1 equal to 15.76% of the total share capital in Novo Nordisk. Novo Nordisk is a healthcare company and a world leader in diabetes care. The company has the broadest diabetes product portfolio in the industry, including the most advanced products within the area of insulin delivery systems. In addition, Novo Nordisk has a leading position within areas such as haemostasis management, growth hormone therapy and hormone replacement therapy. Novo Nordisk manufactures and markets pharmaceutical products and services that make a significant difference to patients, the medical profession and society. With headquarters in Denmark, Novo Nordisk employs approximately 25,800 employees in 79 countries, and markets its products in 179 countries. Novo Nordisk's B shares are listed on the stock exchanges in Copenhagen and London. Its ADRs are listed on the New York Stock Exchange under the symbol 'NVO'. For more information, visit novonordisk.com. FURTHER INFORMATION: Media: Investors: Outside North America: Outside North America: Elin K Hansen Mads Veggerby Lausten Tel (direct): (+45) 4442 3450 Tel (direct): (+45) 4443 7919 ekh@novonordisk.com mlau@novonordisk.com Hans Rommer Tel (direct): (+45) 4442 4765 hrmm@novonordisk.com In North America: In North America: Sean Clements Christian Qvist Frandsen Tel (direct): (+1) 609 514 8316 Tel (direct): (+1) 609 919 7937 secl@novonordisk.com cqfr@novonordisk.com Stock Exchange Announcement no 34 / 2007 SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf of the undersigned, thereunto duly authorized. Date: DECEMBER 7, 2007 NOVO NORDISK A/S --------------------------------------------------- Lars Rebien Sorensen, President and Chief Executive Officer