SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  Schedule 13G


   INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1 (b),
         (c) AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO 13d-2 (b)

                            (Amendment No. _______)*


                                 HemoSense, Inc.
--------------------------------------------------------------------------------
                                (Name of Issuer)


                                  Common Stock
--------------------------------------------------------------------------------
                         (Title of Class of Securities)


                                   423691 10 4
--------------------------------------------------------------------------------
                                 (CUSIP Number)


                                December 31, 2005
--------------------------------------------------------------------------------
             (Date of Event Which Requires Filing of this Statement)

Check the  appropriate box to designate the rule pursuant to which this Schedule
is filed:

         [ ]        Rule 13d-1(b)

         [ ]        Rule 13d-1(c)

         [X]        Rule 13d-1(d)

*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for  any  subsequent   amendment   containing   information  which  would  alter
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).



                               Page 1 of 14 Pages
                       Exhibit Index Contained on Page 12





----------------------------------------------------------                     --------------------------------------
CUSIP NO. 423691 104                                              13 G                                 Page  2 of 14
----------------------------------------------------------                     --------------------------------------


------------ ---------------------------------------------------------------------------------------------------------
                               
1            NAME OF REPORTING PERSONS
             I.R.S. IDENTIFICATION NO. OF ABOVE PERSON (Entities Only).
                      Vanguard V, L.P. ("VVLP")

------------ ---------------------------------------------------------------------------------------------------------
2            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                                                    (a)              (b) X
------------ ---------------------------------------------------------------------------------------------------------
3            SEC USE ONLY

------------ ---------------------------------------------------------------------------------------------------------
4            CITIZENSHIP OR PLACE OF ORGANIZATION

             Delaware
------------ ---------------------------------------------------------------------------------------------------------

                                     5        SOLE VOTING POWER
             NUMBER OF                        699,357 shares, except that Vanguard V Venture Partners, L.L.C.
              SHARES                          ("VVVP"), the general partner of VVLP, may be deemed to have sole
           BENEFICIALLY                       power to vote these shares, and Jack M. Gill ("Gill"), Curtis K. Myers
      OWNED BY EACH REPORTING                 ("Myers"), Clifford H. Higgerson ("Higgerson") and Robert D. Ulrich
              PERSON                          ("Ulrich"), the managing members of VVVP, may be deemed to have shared
               WITH                           power to vote these shares.
                                     -------- ------------------------------------------------------------------------
                                     6        SHARED VOTING POWER
                                              See response to row 5.
                                     -------- ------------------------------------------------------------------------
                                     7        SOLE DISPOSITIVE POWER
                                              699,357 shares, except that VVVP, the general partner of VVLP, may be
                                              deemed to have sole power to dispose of these shares, and Gill, Myers,
                                              Higgerson and Ulrich, the managing members of VVVP, may be deemed to
                                              have shared power to dispose of these shares.
                                     -------- ------------------------------------------------------------------------
                                     8        SHARED DISPOSITIVE POWER
                                              See response to row 7.
------------------------------------ -------- ------------------------------------------------------------------------
9            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
             REPORTING PERSON                                                                       699,357
------------ ---------------------------------------------------------------------------------------------------------
10           CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
             EXCLUDES CERTAIN SHARES (See Instructions)
------------ ---------------------------------------------------------------------------------------------------------
11           PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
                                                                                                    6.3%
------------ ---------------------------------------------------------------------------------------------------------
12           TYPE OF REPORTING PERSON (See Instructions)
                                                                                                    PN
------------ ---------------------------------------------------------------------------------------------------------




----------------------------------------------------------                     --------------------------------------
CUSIP NO. 423691 104                                              13 G                                 Page  3 of 14
----------------------------------------------------------                     --------------------------------------


------------ ---------------------------------------------------------------------------------------------------------
                               
1            NAME OF REPORTING PERSONS
             I.R.S. IDENTIFICATION NO. OF ABOVE PERSON (Entities Only).
                      Vanguard V Venture Partners, L.L.C. ("VVVP")

------------ ---------------------------------------------------------------------------------------------------------
2            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                                                    (a)              (b) X
------------ ---------------------------------------------------------------------------------------------------------
3            SEC USE ONLY

------------ ---------------------------------------------------------------------------------------------------------
4            CITIZENSHIP OR PLACE OF ORGANIZATION

             Delaware
------------ ---------------------------------------------------------------------------------------------------------

                                     5        SOLE VOTING POWER
             NUMBER OF                        699,357 shares, all of which are directly owned by VVLP.  VVVP, the
              SHARES                          general partner of VVLP, may be deemed to have sole power to vote
           BENEFICIALLY                       these shares, and Gill, Myers, Higgerson and Ulrich, the managing
      OWNED BY EACH REPORTING                 members of VVVP, may be deemed to have shared power to vote these
              PERSON                          shares.
               WITH
                                     -------- ------------------------------------------------------------------------
                                     6        SHARED VOTING POWER
                                              See response to row 5.
                                     -------- ------------------------------------------------------------------------
                                     7        SOLE DISPOSITIVE POWER
                                              699,357 shares, all of which are directly owned by VVLP.  VVVP, the
                                              general partner of VVLP, may be deemed to have sole power to dispose
                                              of these shares, and Gill, Myers, Higgerson and Ulrich, the managing
                                              members of VVVP, may be deemed to have shared power to dispose of
                                              these shares.
                                     -------- ------------------------------------------------------------------------
                                     8        SHARED DISPOSITIVE POWER
                                              See response to row 7.
------------------------------------ -------- ------------------------------------------------------------------------
9            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
             REPORTING PERSON                                                                       699,357
------------ ---------------------------------------------------------------------------------------------------------
10           CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
             EXCLUDES CERTAIN SHARES (See Instructions)
------------ ---------------------------------------------------------------------------------------------------------
11           PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
                                                                                                    6.3%
------------ ---------------------------------------------------------------------------------------------------------
12           TYPE OF REPORTING PERSON (See Instructions)
                                                                                                    OO
------------ ---------------------------------------------------------------------------------------------------------




----------------------------------------------------------                     --------------------------------------
CUSIP NO. 423691 104                                              13 G                                 Page  4 of 14
----------------------------------------------------------                     --------------------------------------

------------ ---------------------------------------------------------------------------------------------------------
                               
1            NAME OF REPORTING PERSONS
             I.R.S. IDENTIFICATION NO. OF ABOVE PERSON (Entities Only).

             Jack M. Gill
------------ ---------------------------------------------------------------------------------------------------------
2            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                                                    (a)              (b) X
------------ ---------------------------------------------------------------------------------------------------------
3            SEC USE ONLY

------------ ---------------------------------------------------------------------------------------------------------
4            CITIZENSHIP OR PLACE OF ORGANIZATION

                      U.S. Citizen
------------ ---------------------------------------------------------------------------------------------------------

             NUMBER OF
              SHARES                 5        SOLE VOTING POWER
           BENEFICIALLY                       0 shares.
           OWNED BY EACH
             REPORTING
              PERSON
               WITH
                                     -------- ------------------------------------------------------------------------
                                     6        SHARED VOTING POWER
                                              699,357 shares, all of which are directly owned by VVLP.  VVVP is the
                                              general partner of VVLP, and Gill, a managing member of VVVP, may be
                                              deemed to have shared power to vote these shares.
                                     -------- ------------------------------------------------------------------------
                                     7        SOLE DISPOSITIVE POWER
                                              0 shares.
                                     -------- ------------------------------------------------------------------------
                                     8        SHARED DISPOSITIVE POWER
                                              699,357 shares, all of which are directly owned by VVLP.  VVVP is the
                                              general partner of VVLP, and Gill, a managing member of VVVP, may be
                                              deemed to have shared power to dispose of these shares.
------------------------------------ -------- ------------------------------------------------------------------------
9            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
             REPORTING PERSON                                                                       699,357
------------ ---------------------------------------------------------------------------------------------------------
10           CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
             EXCLUDES CERTAIN SHARES (See Instructions)
------------ ---------------------------------------------------------------------------------------------------------
11           PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
                                                                                                    6.3%
------------ ---------------------------------------------------------------------------------------------------------
12           TYPE OF REPORTING PERSON (See Instructions)                                            IN
------------ ---------------------------------------------------------------------------------------------------------




----------------------------------------------------------                     --------------------------------------
CUSIP NO. 423691 104                                              13 G                                 Page  5 of 14
----------------------------------------------------------                     --------------------------------------

------------ ---------------------------------------------------------------------------------------------------------
                               
1            NAME OF REPORTING PERSONS
             I.R.S. IDENTIFICATION NO. OF ABOVE PERSON (Entities Only).

             Curtis K. Myers
------------ ---------------------------------------------------------------------------------------------------------
2            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                                                    (a)              (b) X
------------ ---------------------------------------------------------------------------------------------------------
3            SEC USE ONLY

------------ ---------------------------------------------------------------------------------------------------------
4            CITIZENSHIP OR PLACE OF ORGANIZATION

                      U.S. Citizen
------------ ---------------------------------------------------------------------------------------------------------

             NUMBER OF
              SHARES                 5        SOLE VOTING POWER
           BENEFICIALLY                       0 shares.
           OWNED BY EACH
             REPORTING
              PERSON
               WITH
                                     -------- ------------------------------------------------------------------------
                                     6        SHARED VOTING POWER
                                              699,357 shares, all of which are directly owned by VVLP.  VVVP is the
                                              general partner of VVLP, and Myers, a managing member of VVVP, may be
                                              deemed to have shared power to vote these shares.
                                     -------- ------------------------------------------------------------------------
                                     7        SOLE DISPOSITIVE POWER
                                              0 shares.
                                     -------- ------------------------------------------------------------------------
                                     8        SHARED DISPOSITIVE POWER
                                              699,357 shares, all of which are directly owned by VVLP.  VVVP is the
                                              general partner of VVLP, and Myers, a managing member of VVVP, may be
                                              deemed to have shared power to dispose of these shares.
------------------------------------ -------- ------------------------------------------------------------------------
9            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
             REPORTING PERSON                                                                       699,357
------------ ---------------------------------------------------------------------------------------------------------
10           CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
             EXCLUDES CERTAIN SHARES (See Instructions)
------------ ---------------------------------------------------------------------------------------------------------
11           PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
                                                                                                    6.3%
------------ ---------------------------------------------------------------------------------------------------------
12           TYPE OF REPORTING PERSON (See Instructions)                                            IN
------------ ---------------------------------------------------------------------------------------------------------




----------------------------------------------------------                     --------------------------------------
CUSIP NO. 423691 104                                              13 G                                 Page  6 of 14
----------------------------------------------------------                     --------------------------------------

------------ ---------------------------------------------------------------------------------------------------------
                               
1            NAME OF REPORTING PERSONS
             I.R.S. IDENTIFICATION NO. OF ABOVE PERSON (Entities Only).

             Clifford H. Higgerson
------------ ---------------------------------------------------------------------------------------------------------
2            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                                                    (a)              (b) X
------------ ---------------------------------------------------------------------------------------------------------
3            SEC USE ONLY

------------ ---------------------------------------------------------------------------------------------------------
4            CITIZENSHIP OR PLACE OF ORGANIZATION

                      U.S. Citizen
------------ ---------------------------------------------------------------------------------------------------------

             NUMBER OF
              SHARES                 5        SOLE VOTING POWER
           BENEFICIALLY                       0 shares.
           OWNED BY EACH
             REPORTING
              PERSON
               WITH
                                     -------- ------------------------------------------------------------------------
                                     6        SHARED VOTING POWER
                                              699,357 shares, all of which are directly owned by VVLP.  VVVP is the
                                              general partner of VVLP, and Higgerson, a managing member of VVVP, may
                                              be deemed to have shared power to vote these shares.
                                     -------- ------------------------------------------------------------------------
                                     7        SOLE DISPOSITIVE POWER
                                              0 shares.
                                     -------- ------------------------------------------------------------------------
                                     8        SHARED DISPOSITIVE POWER
                                              699,357 shares, all of which are directly owned by VVLP.  VVVP is the
                                              general partner of VVLP, and Higgerson, a managing member of VVVP, may
                                              be deemed to have shared power to dispose of these shares.
------------------------------------ -------- ------------------------------------------------------------------------
9            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
             REPORTING PERSON                                                                       699,357
------------ ---------------------------------------------------------------------------------------------------------
10           CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
             EXCLUDES CERTAIN SHARES (See Instructions)
------------ ---------------------------------------------------------------------------------------------------------
11           PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
                                                                                                    6.3%
------------ ---------------------------------------------------------------------------------------------------------
12           TYPE OF REPORTING PERSON (See Instructions)                                            IN
------------ ---------------------------------------------------------------------------------------------------------




----------------------------------------------------------                     --------------------------------------
CUSIP NO. 423691 104                                              13 G                                 Page  7 of 14
----------------------------------------------------------                     --------------------------------------

------------ ---------------------------------------------------------------------------------------------------------
                               
1            NAME OF REPORTING PERSONS
             I.R.S. IDENTIFICATION NO. OF ABOVE PERSON (Entities Only).

             Robert D. Ulrich
------------ ---------------------------------------------------------------------------------------------------------
2            CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                                                    (a)              (b) X
------------ ---------------------------------------------------------------------------------------------------------
3            SEC USE ONLY

------------ ---------------------------------------------------------------------------------------------------------
4            CITIZENSHIP OR PLACE OF ORGANIZATION

                      U.S. Citizen
------------ ---------------------------------------------------------------------------------------------------------

             NUMBER OF
              SHARES                 5        SOLE VOTING POWER
           BENEFICIALLY                       0 shares.
           OWNED BY EACH
             REPORTING
              PERSON
               WITH
                                     -------- ------------------------------------------------------------------------
                                     6        SHARED VOTING POWER
                                              699,357 shares, all of which are directly owned by VVLP.  VVVP is the
                                              general partner of VVLP, and Ulrich, a managing member of VVVP, may be
                                              deemed to have shared power to vote these shares.
                                     -------- ------------------------------------------------------------------------
                                     7        SOLE DISPOSITIVE POWER
                                              0 shares.
                                     -------- ------------------------------------------------------------------------
                                     8        SHARED DISPOSITIVE POWER
                                              699,357 shares, all of which are directly owned by VVLP.  VVVP is the
                                              general partner of VVLP, and Ulrich, a managing member of VVVP, may be
                                              deemed to have shared power to dispose of these shares.
------------------------------------ -------- ------------------------------------------------------------------------
9            AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH
             REPORTING PERSON                                                                       699,357
------------ ---------------------------------------------------------------------------------------------------------
10           CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9)
             EXCLUDES CERTAIN SHARES (See Instructions)
------------ ---------------------------------------------------------------------------------------------------------
11           PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
                                                                                                    6.3%
------------ ---------------------------------------------------------------------------------------------------------
12           TYPE OF REPORTING PERSON (See Instructions)                                            IN
------------ ---------------------------------------------------------------------------------------------------------



---------------------------------                    ---------------------------
CUSIP NO. 423691 104                     13 G                      Page  8 of 14
---------------------------------                    ---------------------------


ITEM 1(A).        NAME OF ISSUER
                  --------------

                  HemoSense, Inc.

ITEM 1(B).        ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES
                  -----------------------------------------------

                  c/o Red Rock Ventures
                  180 Lytton Avenue
                  Palo Alto, CA 94301

ITEM 2(A).        NAME OF PERSONS FILING
                  ----------------------

                  This  Statement  is filed by  Vanguard  V,  L.P.,  a  Delaware
                  limited  partnership  ("VVLP"),  Vanguard V Venture  Partners,
                  L.L.C., a Delaware limited  liability  company  ("VVVP"),  and
                  Jack M. Gill ("Gill"), Curtis K. Myers ("Myers"),  Clifford H.
                  Higgerson  ("Higgerson") and Robert D. Ulrich ("Ulrich").  The
                  foregoing  entities and individuals are collectively  referred
                  to as the "Reporting Persons."

                  VVVP, the general  partner of VVLP, may be deemed to have sole
                  power to vote  and sole  power to  dispose  of  shares  of the
                  issuer  directly  owned by VVLP.  Gill,  Myers,  Higgerson and
                  Ulrich are the  managing  members of VVVP and may be deemed to
                  have  shared  power to vote and  shared  power to  dispose  of
                  shares of the issuer directly owned by VVLP.

ITEM 2(B).        ADDRESS OF PRINCIPAL BUSINESS OFFICE
----------        ------------------------------------

                  The address for each of the Reporting Persons is:

                  Vanguard V, L.P.
                  525 University Avenue, Suite 1200
                  Palo Alto, California  94301

ITEM 2(C)         CITIZENSHIP
                  -----------

                  VVLP is a  Delaware  limited  partnership.  VVVP is a Delaware
                  limited liability company.  Gill, Myers,  Higgerson and Ulrich
                  are United States citizens.

ITEM 2(D) AND (E).    TITLE OF CLASS OF SECURITIES AND CUSIP NUMBER
                      ---------------------------------------------

                  Common Stock
                  CUSIP #423691 10 4

ITEM 3.           Not Applicable.
                  ---------------


ITEM 4.           OWNERSHIP
                  ---------

                  Provide the  following  information  regarding  the  aggregate
                  number and percentage of the class of securities of the issuer
                  identified in Item 1.

                    (a) Amount beneficially owned:
                        --------------------------

                        See Row 9 of cover page for each Reporting Person.

                    (b) Percent of Class:
                        -----------------


---------------------------------                    ---------------------------
CUSIP NO. 423691 104                     13 G                      Page  9 of 14
---------------------------------                    ---------------------------

                        See Row 11 of cover page for each Reporting Person.

                    (c) Number of shares as to which such person has:

                            (i)   Sole power to vote or to direct the vote:
                                  -----------------------------------------

                                  See Row 5 of cover  page  for  each  Reporting
                                  Person.

                            (ii)  Shared power to vote or to direct the vote:
                                  -------------------------------------------

                                  See Row 6 of cover  page  for  each  Reporting
                                  Person.

                            (iii) Sole   power  to  dispose  or  to  direct  the
                                  ----------------------------------------------
                                  disposition of:
                                  ---------------

                                  See Row 7 of cover  page  for  each  Reporting
                                  Person.

                            (iv)  Shared power  to  dispose  or  to  direct  the
                                  ----------------------------------------------
                                  disposition of:
                                  ---------------

                                  See Row 8 of cover  page  for  each  Reporting
                                  Person.


ITEM 5.           OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS
                  --------------------------------------------

                  Not applicable.

ITEM 6.           OWNERSHIP  OF MORE THAN  FIVE  PERCENT  ON  BEHALF OF  ANOTHER
                  --------------------------------------------------------------
                  PERSON.
                  -------

                  Under   certain   circumstances   set  forth  in  the  limited
                  partnership  agreement  of  VVLP,  and the  limited  liability
                  company agreement of VVVP, the general and limited partners or
                  members,  as the case may be, of each of such  entities may be
                  deemed to have the right to  receive  dividends  from,  or the
                  proceeds  from, the sale of shares of the issuer owned by each
                  such entity of which they are a partner or member, as the case
                  may be.

ITEM 7.           IDENTIFICATION  AND  CLASSIFICATION  OF THE  SUBSIDIARY  WHICH
                  --------------------------------------------------------------
                  ACQUIRED THE SECURITY  BEING REPORTED ON BY THE PARENT HOLDING
                  --------------------------------------------------------------
                  COMPANY
                 --------

                  Not applicable.


ITEM 8.           IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP.
                  ----------------------------------------------------------

                  Not applicable.

ITEM 9.           NOTICE OF DISSOLUTION OF GROUP.
                  -------------------------------

                  Not applicable.

ITEM 10.          CERTIFICATION.
                  --------------

                  Not applicable.


---------------------------------                    ---------------------------
CUSIP NO. 423691 104                     13 G                      Page 10 of 14
---------------------------------                    ---------------------------


                                   SIGNATURES
                                   ----------

     After  reasonable  inquiry and to the best of my  knowledge  and belief,  I
certify that the information  set forth in this statement is true,  complete and
correct.


Date:  February 7, 2006

Vanguard V, L.P.                          /s/  Laura Gwodsen
By Vanguard V Venture Partners, LLC       -------------------------------
Its General Partner                       Signature

                                          Laura Gwodsen
                                          -------------------------------
                                          Chief Financial Officer/
                                          Attorney-In-Fact


Jack M. Gill                              /s/  Laura Gwodsen
                                          -------------------------------
                                          Laura Gwodsen
                                          Attorney-In-Fact




Curtis K. Myers                           /s/  Laura Gwodsen
                                          -------------------------------
                                          Laura Gwodsen
                                          Attorney-In-Fact




Clifford H. Higgerson                     /s/  Laura Gwodsen
                                          -------------------------------
                                          Laura Gwodsen
                                          Attorney-In-Fact




Robert D. Ulrich                          /s/  Laura Gwodsen
                                          -------------------------------
                                          Laura Gwodsen
                                          Attorney-In-Fact


The  original  statement  shall be signed by each  person  on whose  behalf  the
statement is filed or his authorized representative.  If the statement is signed
on behalf of a person by his authorized  representative  other than an executive
officer  or   general   partner  of  the   filing   person,   evidence   of  the
representative's  authority to sign on behalf of such person shall be filed with
the  statement,  provided,  however,  that a power of attorney  for this purpose
which is already on file with the Commission may be  incorporated  by reference.
The name and any title of each person who signs the statement  shall be typed or
printed beneath his signature.


---------------------------------                    ---------------------------
CUSIP NO. 423691 104                     13 G                      Page 11 of 14
---------------------------------                    ---------------------------


NOTE:  Schedules  filed in paper format shall include a signed original and five
copies of the  schedule,  including  all exhibits.  See  ss.240.13d-7  for other
parties for whom copies are to be sent.

Attention:  Intentional  misstatements  or omissions of fact constitute  Federal
criminal violations (See 18 U.S.C. 1001)


---------------------------------                    ---------------------------
CUSIP NO. 423691 104                     13 G                      Page 12 of 14
---------------------------------                    ---------------------------


                                  EXHIBIT INDEX
                                  -------------




                                                              Found on
                                                            Sequentially
Exhibit                                                     Numbered Page
-------                                                     -------------

Exhibit A:  Agreement of Joint Filing                            13

Exhibit B:  Power of Attorney                                    14



---------------------------------                    ---------------------------
CUSIP NO. 423691 104                     13 G                      Page 13 of 14
---------------------------------                    ---------------------------


                                    EXHIBIT A
                                    ---------



                            Agreement of Joint Filing
                            -------------------------

     The  undersigned  hereby agree that a single Schedule 13G (or any amendment
thereto)  relating  to the Common  Stock of  HemoSense,  Inc.  shall be filed on
behalf of each of the  undersigned  and that this Agreement shall be filed as an
exhibit to such Schedule 13G.



Date:  February 7, 2006


Vanguard V, L.P.                           /s/  Laura Gwodsen
By Vanguard V Venture Partners, LLC        -------------------------------
Its General Partner                        Signature

                                           Laura Gwodsen
                                           Chief Financial Officer/
                                           Attorney-In-Fact




Jack M. Gill                               /s/  Laura Gwodsen
                                          -------------------------------
                                           Laura Gwodsen
                                           Attorney-In-Fact




Curtis K. Myers                            /s/  Laura Gwodsen
                                          -------------------------------
                                           Laura Gwodsen
                                           Attorney-In-Fact




Clifford H. Higgerson                      /s/  Laura Gwodsen
                                          -------------------------------
                                           Laura Gwodsen
                                           Attorney-In-Fact




Robert D. Ulrich                           /s/  Laura Gwodsen
                                          -------------------------------
                                           Laura Gwodsen
                                           Attorney-In-Fact


---------------------------------                    ---------------------------
CUSIP NO. 423691 104                     13 G                      Page 14 of 14
---------------------------------                    ---------------------------


                                    EXHIBIT B
                                    ---------

                                Power of Attorney
                                -----------------

     Each  of  the  undersigned  entities  and  individuals  (collectively,  the
"Reporting  Persons")  hereby  authorizes  and  designates  Vanguard  V  Venture
Partners,  LLC or such  other  person or entity as is  designated  in writing by
Clifford  Higgerson (the "Designated  Filer") as the beneficial owner to prepare
and file on behalf of such Reporting  Person  individually,  or jointly together
with the other Reporting Persons, any and all reports,  notices,  communications
and other  documents  (including,  but not limited to,  reports on Schedule 13D,
Schedule 13G, Form 13-F,  Form 3, Form 4 and Form 5) that such Reporting  Person
may be  required  to  file  with  the  United  States  Securities  and  Exchange
Commission pursuant to the Securities Act of 1933, as amended (together with the
implementing  regulations thereto, the "Act") and the Securities Exchange Act of
1934,  as amended  (together  with the  implementing  regulations  thereto,  the
"Exchange  Act")  (collectively,  the "Reports")  with respect to each Reporting
Person's  ownership  of, or  transactions  in,  securities  of any entity  whose
securities  are  beneficially  owned  (directly or indirectly) by such Reporting
Person (collectively, the "Companies").

     Each  Reporting  Person hereby  further  authorizes  and  designates  Laura
Gwodsen  (the  "Authorized  Signatory")  to  execute  and file on behalf of such
Reporting Person the Reports and to perform any and all other acts, which in the
opinion of the  Designated  Filer or  Authorized  Signatory  may be necessary or
incidental to the performance of the foregoing powers herein granted.

     The authority of the Designated  Filer and the Authorized  Signatory  under
this Document with respect to each  Reporting  Person shall  continue until such
Reporting  Person is no longer  required to file any Reports with respect to the
Reporting  Person's  ownership  of, or  transactions  in, the  securities of the
Companies, unless earlier revoked in writing. Each Reporting Person acknowledges
that the Designated  Filer and the Authorized  Signatory are not assuming any of
the Reporting Person's  responsibilities  to comply with the Act or the Exchange
Act.

Date:  February 7, 2006


Vanguard V Venture Partners, LLC      /s/  Clifford H. Higgerson
                                     ----------------------------------------
                                     Clifford H. Higgerson, Managing Member



Vanguard V, L.P.                     /s/  Clifford H. Higgerson
                                     ----------------------------------------
                                     Clifford H. Higgerson, Managing Member



Jack M. Gill                         /s/  Jack M. Gill
                                     ----------------------------------------
                                     Jack M. Gill



Curtis K. Myers                      /s/  Curtis K. Myers
                                     ----------------------------------------
                                     Curtis K. Myers



Clifford H. Higgerson                /s/  Clifford H. Higgerson
                                     ----------------------------------------
                                     Clifford H. Higgerson



Robert D. Ulrich                     /s/  Robert D. Ulrich
                                     ----------------------------------------
                                     Robert D. Ulrich