Sensorion Announces its Participation in the Association for Research in Otolaryngology ARO 47th Annual Midwinter Meeting

Regulatory News:

Sensorion (FR0012596468 – ALSEN) a pioneering clinical-stage biotechnology company which specializes in the development of novel therapies to restore, treat and prevent within the field of hearing loss disorders, today announces its participation in the Association for Research in Otolaryngology (ARO) 47^th Annual Midwinter Meeting, taking place on February 03-07, 2024, in Anaheim, California, United States of America.

Laurent Désiré, PhD, Head of Preclinical Development at Sensorion, will give the following presentations during the ARO meeting:

Presentation Type: Symposium on OTOF Therapy Clinical Trial

Title: “SENS-501 Gene Therapy for Autosomal Recessive Non-Syndromic Deafness 9 (DFNB9)”

Date: Saturday February 3, 2024

Time: 10am-12pm PST

Room: Platinum Salon 5

Presentation Type: Podium Presentation, Session 13

Title: “Assessment of an Adeno Associated Vector-Based Gene Therapy (GJB2-GT) for the Non-Syndromic Deafness 1 (DFNB1) in Cynomolgus Monkeys”

Date: Monday February 5, 2024

Time: 2.30pm-2.45pm PST

Room: Platinum Salon 5

Presentation Type: Poster Presentation, Session 1

Title: “Early Players Involved in Both Cisplatin-Induced Ototoxicity and SENS-401 Protection in Intact Organ Cultures”

Poster Number: S61

Date: Saturday February 3, 2024

Time: 1pm-2pm PST

Room: Marquis Ballroom

Presentation Type: Poster Presentation, Session 2

Title: “Surgical Approach for a Safe Intra-Cochlear Injection of AAVs in Macaca Fascicularis”

Poster Number: SU57

Date: Sunday February 4, 2024

Time: 1.15pm-2.15pm PST

Room: Marquis Ballroom

The poster will be co-presented with Pr. Jérôme Nevoux, M.D., Ph.D., Hearing Institute, research center of the Institut Pasteur

Presentation Type: Poster Presentation, Session 2

Title: “Preclinical Development of SENS-501 as a Treatment for the Autosomal Recessive Non-Syndromic Deafness 9 (DFNB9) Using an Adeno Associated Vector-Based Gene Therapy”

Poster Number: SU56

Date: Sunday February 4, 2024

Time: 2.15pm-3.15pm PST

Room: Marquis Ballroom

About Sensorion

Sensorion is a pioneering clinical-stage biotech company, which specializes in the development of novel therapies to restore, treat and prevent hearing loss disorders, a significant global unmet medical need. Sensorion has built a unique R&D technology platform to expand its understanding of the pathophysiology and etiology of inner ear related diseases, enabling it to select the best targets and mechanisms of action for drug candidates.

It has two gene therapy programs aimed at correcting hereditary monogenic forms of deafness, developed in the framework of its broad strategic collaboration focused on the genetics of hearing with the Institut Pasteur. SENS-501 (OTOF-GT) currently being developed in a Phase 1/2 clinical trial, targets deafness caused by mutations of the gene encoding for otoferlin and GJB2-GT targets hearing loss related to mutations in GJB2 gene to potentially address important hearing loss segments in adults and children. The Company is also working on the identification of biomarkers to improve diagnosis of these underserved illnesses.

Sensorion’s portfolio also comprises clinical-stage small molecule programs for the treatment and prevention of hearing loss disorders. Sensorion’s clinical-stage portfolio includes one Phase 2 product: SENS-401 (Arazasetron) progressing in a planned Phase 2 proof of concept clinical study of SENS-401 in Cisplatin-Induced Ototoxicity (CIO) and, with partner Cochlear Limited, in a study of SENS-401 in patients scheduled for cochlear implantation. A Phase 2 study of SENS-401 was also completed in Sudden Sensorineural Hearing Loss (SSNHL) in January 2022.

www.sensorion.com

Label: SENSORION

ISIN: FR0012596468

Mnemonic: ALSEN

Disclaimer

This press release contains certain forward-looking statements concerning Sensorion and its business. Such forward looking statements are based on assumptions that Sensorion considers to be reasonable. However, there can be no assurance that such forward-looking statements will be verified, which statements are subject to numerous risks, including the risks set forth in the 2022 full year financial report published on March 30, 2023, and available on our website and to the development of economic conditions, financial markets and the markets in which Sensorion operates. The forward-looking statements contained in this press release are also subject to risks not yet known to Sensorion or not currently considered material by Sensorion. The occurrence of all or part of such risks could cause actual results, financial conditions, performance or achievements of Sensorion to be materially different from such forward-looking statements. This press release and the information that it contains do not constitute an offer to sell or subscribe for, or a solicitation of an offer to purchase or subscribe for, Sensorion shares in any country. The communication of this press release in certain countries may constitute a violation of local laws and regulations. Any recipient of this press release must inform oneself of any such local restrictions and comply therewith.

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